Momordica charantia: for traditional uses and pharmacological actions

N Ahmad, N Hasan, Z Ahmad, M Zishan… - Journal of Drug …, 2016 - jddtonline.info
Momordica charantia is a plant of the Cucurbitaceae family, is known as bitter melon, karela,
and pare. It grows in tropical areas of the Amazon,, Asia, South America India, East Africa …

Medicinal foodstuffs. XXVII. Saponin constituents of gotu kola (2): structures of new ursane-and oleanane-type triterpene oligoglycosides, centellasaponins B, C, and …

H Matsuda, T Morikawa, H Ueda… - Chemical and …, 2001 - jstage.jst.go.jp
Ursane-and oleanane-type triterpene oligoglycosides, centellasaponins B, C, and D, were
isolated from the aerial parts of Centella asiatica (L.) URBAN cultivated in Sri Lanka together …

[HTML][HTML] Advances in the biosynthesis and molecular evolution of steroidal saponins in plants

Y Li, H Yang, Z Li, S Li, J Li - International Journal of Molecular Sciences, 2023 - mdpi.com
Steroidal saponins are an important type of plant-specific metabolite that are essential for
plants' responses to biotic and abiotic stresses. Because of their extensive pharmacological …

Effects of Momordica charantia on insulin resistance and visceral obesity in mice on high-fat diet

CC Shih, CH Lin, WL Lin - Diabetes research and clinical practice, 2008 - Elsevier
We examined the preventive effect of Momordica charantia L. fruit (bitter melon) on
hyperglycemia and insulin resistance in C57BL/6J mice fed with a high-fat (HF) diet. Firstly …

Inhibition of Increases in Blood Glucose and Serum Neutral Fat by Momordica charantia Saponin Fraction

Y Oishi, T Sakamoto, H Udagawa… - Bioscience …, 2007 - academic.oup.com
Focusing on a functional component of Momordica charantia, saponin, we investigated its
effects on serum glucose and neutral fat levels. Saponin was extracted as a butanol-soluble …

Structure determination, bitterness evaluation and hepatic gluconeogenesis inhibitory activity of triterpenoids from the Momordica charantia fruit

Y Deng, Y Ma, H Liu, Y Zhang, Z Wei, G Liu, X Tang… - Food Chemistry, 2022 - Elsevier
Triterpenoids are hypoglycemic substances and flavor components of Momordica charantia
L., whether their bitterness correlated with hypoglycemic potential remain unknown. Thus …

Trinorcucurbitane and cucurbitane triterpenoids from the roots of Momordica charantia

J Chen, R Tian, M Qiu, L Lu, Y Zheng, Z Zhang - Phytochemistry, 2008 - Elsevier
Five cucurbitacins, kuguacins A–E (1–5), together with three known analogues, 3β, 7β, 25-
trihydroxycucurbita-5,(23E)-diene-19-al (6), 3β, 25-dihydroxy-5β, 19-epoxycucurbita-6,(23E) …

Antiproliferative and hypoglycemic cucurbitane-type glycosides from the fruits of Momordica charantia

PC Hsiao, CC Liaw, SY Hwang, HL Cheng… - Journal of agricultural …, 2013 - ACS Publications
This paper reports that bioassay-guided fractionations of EtOH extract of Momordica
charantia fruits led to the isolation of 15 cucurbitane-type triterpene glycosides including 4 …

In vitro antimicrobial and antioxidant activity of Momordica charantia leaves

G Leelaprakash, JC Rose… - …, 2011 - pharmacophorejournal.com
The aim of the present study was to investigate the in vitro antimicrobial and antioxidant
activity of aqueous and methanol extracts of Momordica charantia leaves. In preliminary …

Kuguacins F–S, cucurbitane triterpenoids from Momordica charantia

JC Chen, WQ Liu, L Lu, MH Qiu, YT Zheng, LM Yang… - Phytochemistry, 2009 - Elsevier
Chemical investigation of the vines and leaves of Momordica charantia resulted in isolation
of fourteen cucurbitane triterpenoids, kuguacins F–S (1–14), including two …