Bile acids are a group of molecular species of acidic steroids with peculiar physical-
chemical and biological characteristics. At high concentrations they become toxic to …

Tauroursodeoxycholic acid (TUDCA) is the taurine conjugate of ursodeoxycholic acid
(UDCA), a US Food and Drug Administration—approved hydrophilic bile acid for the …

Bile acids (BA) are important physiological molecules not only mediating nutrients
absorption and metabolism in peripheral tissues, but exerting neuromodulation effect in the …

Bile acids, a structurally related group of molecules derived from cholesterol, have a long
history as therapeutic agents in medicine, from treatment for primarily ocular diseases in …

Objective: Amyotrophic lateral sclerosis is a progressive degenerative disease, which
typically leads to death in 3 to 5 years. Neuronal cell death offers a potential target for …

Objectives In this study, we study the transplantation of tauroursodeoxycholic acid (TUDCA)‐
induced M2‐phenotype (M2) macrophages and their ability to promote anti …

Background Bile acids are steroid acids found predominantly in the bile of mammals. The
bile acid conjugate tauroursodeoxycholic acid (TUDCA) is a neuroprotective agent in …

Proteostasis (protein homeostasis) is critical for cellular as well as organismal survival. It is
strictly regulated by multiple conserved pathways including the ubiquitin-proteasome …

Intracerebral hemorrhage (ICH) is a form of stroke, characterized by high morbidity and
mortality and currently lacks specific therapy. ICH leads to endoplasmic reticulum (ER) …

This study aimed to investigate the anti-inflammatory effects of tauroursodeoxycholic acid
(TUDCA) after spinal cord injury (SCI) in rats. We induced an inflammatory process in RAW …