Today's challenge for precision medicine involves the integration of the impact of molecular
clocks on drug pharmacokinetics, toxicity, and efficacy toward personalized chronotherapy …

Cardiovascular disease (CVD) is the leading cause of death globally for men and women.
Premenopausal women have a lower incidence of hypertension and other cardiovascular …

Aims The aim of this study was to test whether current and past night shift work was
associated with incident atrial fibrillation (AF) and whether this association was modified by …

Daily eating/fasting cycles synchronise circadian peripheral clocks, involved in the
regulation of the cardiovascular system. However, the associations of daily meal and fasting …

Aims Growing evidence suggests that poor sleep health is associated with cardiovascular
risk. However, research in this area often relies upon recollection dependent questionnaires …

Microglia play a critical role in maintaining neural function. While microglial activity follows a
circadian rhythm, it is not clear how this intrinsic clock relates to their function, especially in …

Background Although the association between shift work and individual cardiometabolic
diseases has been well studied, its role in the progression to cardiometabolic multimorbidity …

Sex as a biological variable is the focus of much literature and has been emphasized by the
National Institutes of Health, in part, to remedy a long history of male-dominated studies in …

Melatonin (MLT) is a neurohormone that is regulated by the circadian clock and plays
multifunctional roles in numerous neurodegenerative disorders, such as Alzheimer's …

Sleep and the circadian clock are intertwined and have persisted throughout history. The
suprachiasmatic nucleus (SCN) orchestrates sleep by controlling circadian (Process C) and …