Imatinib induces durable hematologic and cytogenetic responses in patients with accelerated phase chronic myeloid leukemia: results of a phase 2 study

M Talpaz, RT Silver, BJ Druker… - Blood, The Journal …, 2002 - ashpublications.org
Chronic myelogenous leukemia (CML) is caused by expression of the BCR-ABL tyrosine
kinase oncogene, the product of the t (9; 22) Philadelphia translocation. Patients with CML in …

Detection and quantification of residual disease in chronic myelogenous leukemia

A Hochhaus, A Weisser, P La Rosee, M Emig… - Leukemia, 2000 - nature.com
The degree of tumor load reduction after therapy is an important prognostic factor for
patients with CML. Conventional metaphase analysis has been considered to be the 'gold …

Allogeneic stem cell transplantation for chronic myeloid leukemia

J Barrett - Seminars in hematology, 2003 - Elsevier
Allogeneic stem cell transplantation (SCT) plays a central role in chronic myeloid leukemia
(CML) because it remains the only treatment with proven curative potential. For this reason …

Long-term outcome and quality of life of patients who are alive and in complete remission more than two years after allogeneic and syngeneic stem cell transplantation

N Worel, D Biener, P Kalhs, M Mitterbauer… - Bone marrow …, 2002 - nature.com
We assessed long-term outcome in 155 patients who had undergone an
allogeneic/syngeneic stem cell transplant (SCT) and were in complete remission for more …

Matched unrelated or matched sibling donors result in comparable outcomes after non-myeloablative HSCT in patients with AML or MDS

M Robin, R Porcher, L Ades, N Boissel… - Bone marrow …, 2013 - nature.com
The impact of allelic HLA matching in patients with AML and myelodysplastic syndrome
(MDS) who receive allogeneic PBSC after a reduced-intensity conditioning (RIC) regimen is …

Survival of patients with chronic myelocytic leukemia: comparisons of estimates from clinical trial settings and population‐based cancer registries

D Pulte, A Gondos, MT Redaniel, H Brenner - The Oncologist, 2011 - academic.oup.com
Introduction. The survival of patients with chronic myelocytic leukemia (CML) has improved
during the past decades. However, there have been discrepancies between results reported …

Predictors of 1-year survival assessed at the time of bone marrow transplantation

G Chang, J Orav, MY Tong, JH Antin - Psychosomatics, 2004 - Elsevier
The purpose of this prospective cohort study was to identify pretransplant and transplant
predictors of 1-year survival after allogeneic hematopoietic stem cell transplantation (HSCT) …

Depression, cigarette smoking, and hematopoietic stem cell transplantation outcome

G Chang, E John Orav, T McNamara, MY Tong… - Cancer, 2004 - Wiley Online Library
BACKGROUND The relationships between psychological and behavioral variables and
patient outcomes after hematopoietic stem cell transplantation (HSCT) are not known …

Chronic myeloid leukemia: pathophysiology, diagnostic parameters, and current treatment concepts

C Sillaber, M Mayerhofer, H Agis, V Sagaster… - Wiener Klinische …, 2003 - Springer
Chronic myeloid leukemia (CML) is a stem cell disease characterized by excessive
accumulation of clonal myeloid (precursor) cells in hematopoietic tissues. CML cells display …

Unrelated cord blood transplantation in CML: Japan Cord Blood Bank Network analysis

T Nagamura-Inoue, S Kai, H Azuma… - Bone marrow …, 2008 - nature.com
We analysed 86 patients with CML who received unrelated cord blood transplantation
(UCBT), identified through a registry of the Japan Cord Blood Bank Network. At …