[HTML][HTML] A potential therapeutic target in traditional Chinese medicine for ulcerative colitis: Macrophage polarization

Z Yang, S Lin, W Feng, Y Liu, Z Song, G Pan… - Frontiers in …, 2022 - frontiersin.org
Intestinal macrophages are the main participants of intestinal immune homeostasis and
intestinal inflammation. Under different environmental stimuli, intestinal macrophages can …

[HTML][HTML] Macrophage polarization in inflammatory bowel disease

K Zhang, J Guo, W Yan, L Xu - Cell Communication and Signaling, 2023 - Springer
The growing prevalence of inflammatory bowel disease (IBD) has encouraged research
efforts, which have contributed to gradual improvements in our understanding of IBD …

Astragaloside Ⅳ alleviates ulcerative colitis by regulating the balance of Th17/Treg cells

Y Zhong, W Liu, Y Xiong, Y Li, Q Wan, W Zhou, H Zhao… - Phytomedicine, 2022 - Elsevier
Background Restoring immune homeostasis by targeting the Th17/Treg response is a
potentially valuable therapeutic strategy for ulcerative colitis (UC). Astragaloside IV (AS-Ⅳ) …

[HTML][HTML] Astragalus Mongholicus: A review of its anti-fibrosis properties

F Gong, R Qu, Y Li, Y Lv, J Dai - Frontiers in Pharmacology, 2022 - frontiersin.org
Background: Fibrosis-related diseases (FRD) include cerebral fibrosis, pulmonary fibrosis,
cardiac fibrosis, liver fibrosis, renal fibrosis, peritoneal fibrosis, etc. The effects of fibrosis can …

[HTML][HTML] Traditional Chinese medicine and natural products: potential approaches for inflammatory bowel disease

S Yuan, Y Li, J Li, JC Xue, Q Wang, XT Hou… - Frontiers in …, 2022 - frontiersin.org
Inflammatory bowel disease (IBD) is a rare, recurrent, and intractable inflammation
obstruction of the stomach tract, usually accompanied by inflammation of cell proliferation …

[HTML][HTML] Fermented Astragalus and its metabolites regulate inflammatory status and gut microbiota to repair intestinal barrier damage in dextran sulfate sodium …

J Li, Y Ma, X Li, Y Wang, Z Huo, Y Lin, J Li… - Frontiers in …, 2022 - frontiersin.org
Fermentation represents an efficient biotechnological approach to increase the nutritional
and functional potential of traditional Chinese medicine. In this study, Lactobacillus …

Quercetin serves as the major component of Xiang-lian Pill to ameliorate ulcerative colitis via tipping the balance of STAT1/PPARγ and dictating the alternative …

H Zhou, C Yang, J Li, Y He, Y Huang, R Qin… - Journal of …, 2023 - Elsevier
Abstract Ethnopharmacological relevance The traditional Chinese herbal formula, Xiang-
lian Pill (XLP), is commonly prescribed for ulcerative colitis (UC) patients to relieve their …

Astragalus polysaccharide alleviates ulcerative colitis by regulating the balance of Tfh/Treg cells

Y Zhong, Q Xiao, Z Kang, J Huang, W Ge… - International …, 2022 - Elsevier
The immunomodulatory function of natural active ingredients has long been a focus of
scientific research, with recent hotspots reporting targeted modulation of the follicular helper …

Traditional Chinese medicine in regulating macrophage polarization in immune response of inflammatory diseases

S Chen, J Zeng, R Li, Y Zhang, Y Tao, Y Hou… - Journal of …, 2024 - Elsevier
Ethnopharmacological relevance Numerous studies have demonstrated that various
traditional Chinese medicines (TCMs) exhibit potent anti-inflammatory effects against …

LncRNA-HOXC-AS2 regulates tumor-associated macrophage polarization through the STAT1/SOCS1 and STAT1/CIITA pathways to promote the progression of non …

C Yin, J Li, S Li, X Yang, Y Lu, C Wang, B Liu - Cellular Signalling, 2024 - Elsevier
Tumor-associated macrophages (TAMs) mainly exhibit the characteristics of M2-type
macrophages, and the regulation of TAM polarization is a new target for cancer therapy …