The inflammation is the protective response of the body against various harmful stimuli;
however, the aberrant and inappropriate activation tends to become harmful. The acute …

Calcitriol, the hormonally active form of vitamin D, is being evaluated in clinical trials as an
anti-cancer agent. Calcitriol exerts multiple anti-proliferative, pro-apoptotic, and pro …

It is estimated that 1 billion people around the world are vitamin D deficient. Vitamin D
deficiency has been linked to various inflammatory diseases. However, the mechanism by …

Gastric cancer is a leading cause of cancer death worldwide. Diet, obesity, smoking and
chronic infections, especially with Helicobacter pylori, contribute to stomach cancer …

Background The production of peroxide and superoxide is an inevitable consequence of
aerobic metabolism, and while these particular'reactive oxygen species'(ROSs) can exhibit a …

Activation of innate immune systems including Toll‐like receptor (TLR) signaling is a key in
chronic liver disease. Recent studies suggest that gut microflora‐derived bacterial products …

Human mesenchymal stem cells (hMSCs)-derived extracellular vesicles (EVs) have been
known to possess the features of the origin cell with nano size and have shown therapeutic …

Exposure to a variety of toxins and/or infectious agents leads to disease, degeneration and
death, often characterised by circumstances in which cells or tissues do not merely die and …

Calcitriol (1, 25-dihydroxyvitamin D3), the biologically most active form of vitamin D,
maintains calcium homeostasis through its actions in intestine, bone, kidneys, and the …

Chemoprevention, a relatively new and promising strategy to prevent cancer, is defined as
the use of natural dietary compounds and/or synthetic substances to block, inhibit, reverse …