The Ser and Thr kinase AKT, also known as protein kinase B (PKB), was discovered 25
years ago and has been the focus of tens of thousands of studies in diverse fields of biology …

Macrophages become activated initiating innate immune responses. Depending on the
signals, macrophages obtain an array of activation phenotypes, described by the broad …

The innate immune system is central for the maintenance of tissue homeostasis and quickly
responds to local or systemic perturbations by pathogenic or sterile insults. This rapid …

This review will briefly outline the major signaling pathways in PMA-activated neutrophils.
PMA is widely used to understand neutrophil pathways and formation of NETs. PMA …

Abstract The PI3K/AKT signaling pathway is an essential node in mammalian cells that
controls cell growth, migration, proliferation, and metabolism. During the last decade, a …

Macrophage apoptosis and the ability of macrophages to clean up dead cells, a process
called efferocytosis, are crucial determinants of atherosclerosis lesion progression and …

Elevating Akt activation is an obvious clinical strategy to prevent progressive neuronal death
in neurological diseases. However, this endeavor has been hindered because of the lack of …

Chemotaxis, or directed migration of cells along a chemical gradient, is a highly coordinated
process that involves gradient sensing, motility, and polarity. Most of our understanding of …

Neurodevelopmental biology, coupled with the application of advanced histological,
imaging, molecular, cellular, biochemical, and genetic approaches, has provided new …

With the increasing market demand for high-performance lithium-ion batteries with high-
capacity electrode materials, reducing the irreversible capacity loss in the initial cycle and …