Introduction: Acridine derivatives have been extensively explored as potential therapeutic
agents for the treatment of a number of diseases, such as cancer, Alzheimer's, and bacterial …

Acridine and acridone are heterocyclic organic compounds with nitrogen atoms in their
molecular structure. Over the years, acridine and acridone derivatives have been …

The discovery of new effective DNA-targeted antitumor agent is needed because of their
clinical significance. As acridines can intercalate into DNA and benzimidazoles have the …

Heterocycles have long been the focus of intensive study in attempts to develop novel
therapeutic compounds, and acridine, a polynuclear nitrogen molecule containing a …

This review summarizes advances in the chemistry of acridines concerning properties,
isolation of natural products possessing the acridine ring as a partial structure, new …

Understanding the dsDNA· EG binding interaction is important because the EvaGreen (EG)
dye is increasingly used in real-time quantitative polymerase chain reaction, high resolution …

A facile and efficient approach for the synthesis of a variety of acridines via the tandem
coupling/cyclization of substituted 2-bromobenzaldehydes and anilines is described. The …

A series of N-alkylated benzimidazolium salts based on 9-substituted acridine has been
synthesized and subsequently converted into the corresponding Ag (I) carbene complexes …

Colorectal cancer (CRC) ranks as the third most common primary malignancy.
Epidemiological data projected approximately 1.9 million new cases and 0.9 million deaths …

A series of 9-benzylamino acridine derivatives were synthesized as an extension of our
discovery of acridine antitumor agents. Most of these acridine compounds displayed good …