Growing evidence suggests a consistent association between atrial fibrillation (AF) and
cognitive impairment and dementia that is independent of clinical stroke. This report from the …

The incidence of stroke and dementia are diverging across the world, rising for those in low-
and middle-income countries and falling in those in high-income countries. This suggests …

Introduction Stroke is an established risk factor for all-cause dementia, though meta-
analyses are needed to quantify this risk. Methods We searched Medline, PsycINFO, and …

Cognitive impairment and dementia are major medical, social, and economic public health
issues worldwide with significant implications for life quality in older adults. The leading …

Blood-brain barrier (BBB) separates the systemic circulation and the brain, regulating
transport of most molecules to protect the brain microenvironment. Multiple structural and …

Adult-onset leukodystrophies and genetic leukoencephalopathies comprise a diverse group
of neurodegenerative disorders of white matter with a wide age of onset and phenotypic …

Subcortical small-vessel disease (SSVD) is a disorder well characterized from the clinical,
imaging, and neuropathological viewpoints. SSVD is considered the most prevalent …

In the last years, there has been a significant growth in the literature exploring the
pathophysiology of vascular cognitive impairment (VCI). As an “umbrella term” …

Cerebrovascular diseases are well established causes of cognitive impairment. Different
etiologic entities, such as vascular dementia (VaD), vascular cognitive impairment …

European Heart Rhythm Association (EHRA)/Heart Rhythm Society (HRS)/Asia Pacific
Heart Rhythm Society (APHRS)/Latin American Heart Rhythm Society (LAHRS) expert …