A review of partial volume correction techniques for emission tomography and their applications in neurology, cardiology and oncology

K Erlandsson, I Buvat, PH Pretorius… - Physics in Medicine …, 2012 - iopscience.iop.org
Accurate quantification in PET and SPECT requires correction for a number of physical
factors, such as photon attenuation, Compton scattering and random coincidences (in PET) …

[HTML][HTML] Imaging the acute respiratory distress syndrome: past, present and future

L Bitker, D Talmor, JC Richard - Intensive Care Medicine, 2022 - Springer
In patients with the acute respiratory distress syndrome (ARDS), lung imaging is a
fundamental tool in the study of the morphological and mechanistic features of the lungs …

First results on kinetic modelling and parametric imaging of dynamic 18F-FDG datasets from a long axial FOV PET scanner in oncological patients

H Sari, C Mingels, I Alberts, J Hu, D Buesser… - European journal of …, 2022 - Springer
Purpose To investigate the kinetics of 18 F-fluorodeoxyglucose (18 F-FDG) by positron
emission tomography (PET) in multiple organs and test the feasibility of total-body …

A randomised, placebo-controlled study of omipalisib (PI3K/mTOR) in idiopathic pulmonary fibrosis

PT Lukey, SA Harrison, S Yang, Y Man… - European …, 2019 - Eur Respiratory Soc
Phosphatidylinositol 3-kinases (PI3Ks) and mammalian target of rapamycin (mTOR) play a
role in the pathogenesis of idiopathic pulmonary fibrosis (IPF). Omipalisib (GSK2126458) is …

Type I collagen–targeted PET probe for pulmonary fibrosis detection and staging in preclinical models

P Désogère, LF Tapias, LP Hariri, NJ Rotile… - Science translational …, 2017 - science.org
Pulmonary fibrosis is scarring of the lungs that can arise from radiation injury, drug toxicity,
environmental or genetic causes, and for unknown reasons [idiopathic pulmonary fibrosis …

[HTML][HTML] Clinical quantification of the integrin αvβ6 by [18F]FB-A20FMDV2 positron emission tomography in healthy and fibrotic human lung (PETAL Study)

PT Lukey, C Coello, R Gunn, C Parker… - European Journal of …, 2020 - Springer
Purpose The RGD-integrin, αvβ6, plays a role in the pathogenesis of pulmonary fibrosis
through activation of transforming growth factor beta (TGFβ). This study sought to quantify …

[HTML][HTML] Pulmonary 18F-FDG uptake helps refine current risk stratification in idiopathic pulmonary fibrosis (IPF)

T Win, NJ Screaton, JC Porter, B Ganeshan… - European journal of …, 2018 - Springer
Purpose There is a lack of prognostic biomarkers in idiopathic pulmonary fibrosis (IPF)
patients. The objective of this study is to investigate the potential of 18 F-FDG-PET/CT to …

Quantification of lung PET images: challenges and opportunities

DL Chen, J Cheriyan, ER Chilvers… - Journal of Nuclear …, 2017 - Soc Nuclear Med
Millions of people are affected by respiratory diseases, leading to a significant health burden
globally. Because of the current insufficient knowledge of the underlying mechanisms that …

[HTML][HTML] Areas of normal pulmonary parenchyma on HRCT exhibit increased FDG PET signal in IPF patients

T Win, BA Thomas, T Lambrou, BF Hutton… - European journal of …, 2014 - Springer
Purpose Patients with idiopathic pulmonary fibrosis (IPF) show increased PET signal at sites
of morphological abnormality on high-resolution computed tomography (HRCT). The …

Improved correction for the tissue fraction effect in lung PET/CT imaging

BF Holman, V Cuplov, L Millner… - Physics in Medicine …, 2015 - iopscience.iop.org
Recently, there has been an increased interest in imaging different pulmonary disorders
using PET techniques. Previous work has shown, for static PET/CT, that air content in the …