The brain is a singular organ of unique biological complexity that serves as the command
center for cognitive and motor function. As such, this specialized system also possesses a …

Abstract α-Enolase 1 (ENO1) is a critical glycolytic enzyme whose aberrant expression
drives the pathogenesis of various cancers. ENO1 has been indicated as having additional …

Members of the mitochondrial carrier family (SLC25) transport a variety of compounds
across the inner membrane of mitochondria. These transport steps provide building blocks …

Pancreatic cancer is an aggressive malignancy with changes in the tumor
microenvironment. Here, we demonstrate that PINK1 and PARK2 suppressed pancreatic …

Ferroptosis is a recently discovered form of programmed cell death, but its regulatory
mechanisms are not fully understood. In the current study, we reported that the BRD7-P53 …

Mammalian cells use a specialized and complex machinery for the removal of altered
proteins or dysfunctional organelles. Such machinery is part of a mechanism called …

This review highlights the biological importance of mitochondrial energy metabolism and the
applications of multiple optical/electrochemical approaches to determine energy …

Iron is an essential element for the development and functionality of the brain, and
anomalies in its distribution and concentration in brain tissue have been found to be …

Mitochondria are biosynthetic, bioenergetic, and signaling organelles which are critical for
physiological adaptations and cellular stress responses to the environment. Various …

Ferroptosis is defined as an iron-dependent regulated form of cell death driven by lipid
peroxidation. In the past decade, it has been implicated in the pathogenesis of various …