Stem cell‐based tooth and periodontal regeneration

L Hu, Y Liu, S Wang - Oral diseases, 2018 - Wiley Online Library
Currently regeneration of tooth and periodontal damage still remains great challenge. Stem
cell‐based tissue engineering raised novel therapeutic strategies for tooth and periodontal …

Dental pulp regeneration via cell homing

S Eramo, A Natali, R Pinna… - International endodontic …, 2018 - Wiley Online Library
The typical treatment for irreversibly inflamed/necrotic pulp tissue is root canal treatment. As
an alternative approach, regenerative endodontics aims to regenerate dental pulp‐like …

Cell-based regenerative endodontics for treatment of periapical lesions: a randomized, controlled phase I/II clinical trial

C Brizuela, G Meza, D Urrejola… - Journal of Dental …, 2020 - journals.sagepub.com
A randomized controlled phase I/II clinical trial was designed to evaluate the safety and
efficacy of encapsulated human umbilical cord mesenchymal stem cells in a plasma-derived …

Clinical cell‐based versus cell‐free regenerative endodontics: clarification of concept and term

LM Lin, GTJ Huang, A Sigurdsson… - International …, 2021 - Wiley Online Library
There is no consensus on the true meaning of clinical regenerative endodontics, and there
is confusion over the concept and the term. Commonly used terms include revitalization and …

Pulp regeneration: current approaches and future challenges

J Yang, G Yuan, Z Chen - Frontiers in physiology, 2016 - frontiersin.org
Regenerative endodontics aims to replace inflamed/necrotic pulp tissues with regenerated
pulp-like tissues to revitalize teeth and improve life quality. Pulp revascularization case …

Current advance and future prospects of tissue engineering approach to dentin/pulp regenerative therapy

T Gong, BC Heng, ECM Lo, C Zhang - Stem Cells International, 2016 - Wiley Online Library
Recent advances in biomaterial science and tissue engineering technology have greatly
spurred the development of regenerative endodontics. This has led to a paradigm shift in …

Survival of the apical papilla and its resident stem cells in a case of advanced pulpal necrosis and apical periodontitis

V Chrepa, B Pitcher, MA Henry, A Diogenes - Journal of endodontics, 2017 - Elsevier
Introduction Apical papilla represents a source of an enriched mesenchymal stem cell
(MSC) population (stem cells of the apical papilla [SCAPs]) that modulates root development …

Personalized cell therapy for pulpitis using autologous dental pulp stem cells and leukocyte platelet-rich fibrin: a case report

G Meza, D Urrejola, N Saint Jean, C Inostroza… - Journal of …, 2019 - Elsevier
Introduction Regenerative endodontic procedures have emerged as a new treatment. The
aim of this case report was to describe a regenerative autologous cellular therapy using …

A Miniature Swine Model for Stem Cell-Based De Novo Regeneration of Dental Pulp and Dentin-Like Tissue

X Zhu, J Liu, Z Yu, CA Chen, H Aksel… - … Engineering Part C …, 2018 - liebertpub.com
The goal of this study was to establish mini-swine as a large animal model for stem cell-
based pulp regeneration studies. Swine dental pulp stem cells (sDPSCs) were isolated from …

[HTML][HTML] Antibiofilm and immunomodulatory resorbable nanofibrous filing for dental pulp regenerative procedures

MG da Costa Sousa, GC de Almeida, DCM Mota… - Bioactive Materials, 2022 - Elsevier
Multifunctional scaffolds with host defense peptides designed for regenerative endodontics
are desirable nanobiotechnological tools for dentistry. Here, different scaffolds were tested …