There is increasing evidence that oxidative stress is implicated in the development of
bronchopulmonary dysplasia. Several important factors contribute to augmented oxidative …

Contents Free radicals are highly reactive oxidizing agents containing one or more unpaired
electrons. Both in human and veterinary neonathology, it is generally accepted that oxidative …

Pulmonary oxidant stress plays an important pathogenetic role in disease conditions
including acute lung injury/adult respiratory distress syndrome (ALI/ARDS), hyperoxia …

Oxygen radicals are considered to be major causative factors in many illnesses of preterm
infants. This article reviews the antioxidant defenses in immature animals and preterm …

Nutrition has a profound influence on free radical production and lipid peroxidation in living
organisms. Vitamins E, C, and A are nutrients that function as antioxidants in part by reacting …

An increasing number of studies in cell cultures, isolated perfused hearts, and intact animal
preparations purport to show the significance of free radical production in the …

Free radicals have been implicated in the pathogenesis of a wide spectrum of human
diseases. Premature infants are probably developmentally unprepared for extrauterine life in …

Extracellular superoxide dismutase (EC-SOD) is an abundant antioxidant in the lung and
vascular walls. Previous studies have shown that EC-SOD attenuates lung injury in a …

To determine whether overexpression of antioxidant enzymes in lung epithelial cells
prevents damage from oxidant injury, stable cell lines were generated with complementary …

BACKGROUND: Exposure of animals to hyperoxia causes lung injury, characterized by
diffuse alveolar damage and exudation of plasma into the alveolar space. Reactive oxygen …