This review takes into consideration the principal vaccines developed against the SARS-
CoV-2 in this unprecedented period of Covid-19 pandemic. We evaluated the mechanism of …

Due to the high prevalence and long incubation periods often without symptoms, the severe
acute respiratory syndrome coronavirus-2 (SARS-CoV-2) has infected millions of individuals …

Highlights•mRNA vaccines address many of the weaknesses of conventional vaccine
types.•Innovations in recent years revolutionized the applicability of mRNA vaccines.•mRNA …

Vaccination is still the most cost-effective way to combat infectious illnesses. Conventional
vaccinations may have low immunogenicity and, in most situations, only provide partial …

Abstract mRNA vaccines represent a promising alternative to conventional vaccine
approaches because of their high potency, capacity for rapid development and potential for …

Two decades ago successful transfection of antigen presenting cells (APC) in vivo was
demonstrated which resulted in the induction of primary adaptive immune responses. Due to …

This review summarizes the use of high-voltage electrical pulses (HVEPs) in clinical
oncology to treat solid tumors with irreversible electroporation (IRE) and …

Various strategies have been designed to contain the COVID-19 pandemic. Among them,
vaccine development is high on the agenda in spite of the unknown duration of the …

This review will explore the four major pillars required for design and development of an
saRNA vaccine: Antigen design, vector design, non-viral delivery systems, and …

Research on tumor immunotherapy has made tremendous progress in the past decades,
with numerous studies entering the clinical evaluation. The cancer vaccine is considered a …