Hypervirulent Klebsiella pneumoniae – clinical and molecular perspectives

JE Choby, J Howard‐Anderson… - Journal of internal …, 2020 - Wiley Online Library
Hypervirulent Klebsiella pneumoniae (hvKp) has emerged as a concerning global
pathogen. hvKp is more virulent than classical K. pneumoniae (cKp) and capable of causing …

[HTML][HTML] Virulence factors in hypervirulent Klebsiella pneumoniae

J Zhu, T Wang, L Chen, H Du - Frontiers in microbiology, 2021 - frontiersin.org
Hypervirulent Klebsiella pneumoniae (hvKP) has spread globally since first described in the
Asian Pacific Rim. It is an invasive variant that differs from the classical K. pneumoniae …

[HTML][HTML] Klebsiella pneumoniae: an increasing threat to public health

CY Effah, T Sun, S Liu, Y Wu - Annals of clinical microbiology and …, 2020 - Springer
Objectives This review fills the paucity of information on K. pneumoniae as a nosocomial
pathogen by providing pooled data on epidemiological risk factors, resistant trends and …

[HTML][HTML] Genomic surveillance for hypervirulence and multi-drug resistance in invasive Klebsiella pneumoniae from South and Southeast Asia

KL Wyres, TNT Nguyen, MMC Lam, LM Judd… - Genome medicine, 2020 - Springer
Background Klebsiella pneumoniae is a leading cause of bloodstream infection (BSI).
Strains producing extended-spectrum beta-lactamases (ESBLs) or carbapenemases are …

[HTML][HTML] Aerobactin seems to be a promising marker compared with unstable RmpA2 for the identification of hypervirulent carbapenem-resistant Klebsiella …

C Shankar, S Basu, B Lal, S Shanmugam… - Frontiers in Cellular …, 2021 - frontiersin.org
Background: The incidence of hypervirulent (hv) carbapenem resistant (CR) K. pneumoniae
(Kp) is increasing globally among various clones and is also responsible for nosocomial …

[HTML][HTML] Neonatal Sepsis: The Impact of Carbapenem-Resistant and Hypervirulent Klebsiella pneumoniae

S Mukherjee, S Mitra, S Dutta, S Basu - Frontiers in Medicine, 2021 - frontiersin.org
The convergence of a vulnerable population and a notorious pathogen is devastating, as
seen in the case of sepsis occurring during the first 28 days of life (neonatal period). Sepsis …

Yersiniabactin contributes to overcoming zinc restriction during Yersinia pestis infection of mammalian and insect hosts

SL Price, V Vadyvaloo, JK DeMarco… - Proceedings of the …, 2021 - National Acad Sciences
Yersinia pestis causes human plague and colonizes both a mammalian host and a flea
vector during its transmission cycle. A key barrier to bacterial infection is the host's ability to …

The making of hypervirulent Klebsiella pneumoniae

P Dai, D Hu - Journal of Clinical Laboratory Analysis, 2022 - Wiley Online Library
Klebsiella pneumoniae is a notorious bacterium in clinical practice. Virulence, carbapenem‐
resistance and their convergence among K. pneumoniae are extensively discussed in this …

Characterisation of virulence genes associated with pathogenicity in Klebsiella pneumoniae

PA Remya, M Shanthi, U Sekar - Indian journal of medical microbiology, 2019 - Elsevier
Purpose: This study was undertaken to characterise the virulence factors in clinical strains of
Klebsiella pneumoniae and analyse their association with various infections caused and …

Comparative analysis of Klebsiella pneumoniae strains isolated in 2012–2016 that differ by antibiotic resistance genes and virulence genes profiles

AI Lev, EI Astashkin, AA Kislichkina… - Pathogens and global …, 2018 - Taylor & Francis
The antibacterial resistance and virulence genotypes and phenotypes of 148 non-duplicate
Klebsiella pneumoniae strains collected from 112 patients in Moscow hospitals in 2012 …