Significance: Angiogenesis, the growth of new blood vessels from existing vessels, is an
important aspect of the repair process. Restoration of blood flow to damaged tissues …

Excessive connective tissue accumulation, a hallmark of hypertrophic scaring, results in
progressive deterioration of the structure and function of organs. It can also be seen during …

In addition to its antimicrobial activity, the skin-derived antimicrobial peptide human β-
defensin-3 (hBD-3) promotes keratinocyte proliferation and migration to initiate the wound …

Vascular endothelial growth factor (VEGF-A) is known for its effects on endothelial cells and
as a positive mediator of angiogenesis. VEGF is thought to promote repair of cutaneous …

Vascular endothelial growth factor‐A (VEGF‐A) is strongly up‐regulated in wounded
cutaneous tissue and promotes repair‐associated angiogenesis. However, little is known …

Angiogenesis is a critical step of wound healing, and its failure leads to chronic wounds. The
idea of restoring blood flow to the damaged tissues by promoting neo-angiogenesis is …

Activation of an innate immune response is among the first lines of defense after tissue
injury. Restoring blood flow to the site of injured tissue is often a necessary prerequisite for …

PURPOSE: To determine whether bevacizumab can reduce bleb failure in patients
undergoing first-time trabeculectomy for primary open-angle glaucoma (POAG) or chronic …

Significance: The proangiogenic mediator vascular endothelial growth factor (VEGF) plays
an important role in cutaneous wound repair. Most of the work on VEGF and wound healing …

Vascular endothelial growth factor (VEGF-A), a potent stimulus for angiogenesis, is up-
regulated in the skin after wounding. Although studies have shown that VEGF is important …