Emerging COVID-19 variants and their impact on SARS-CoV-2 diagnosis, therapeutics and vaccines
The emergence of novel and evolving variants of SARS-CoV-2 has fostered the need for
change in the form of newer and more adaptive diagnostic methods for the detection of …
change in the form of newer and more adaptive diagnostic methods for the detection of …
Respiratory syncytial virus prevention within reach: the vaccine and monoclonal antibody landscape
Respiratory syncytial virus is the second most common cause of infant mortality and a major
cause of morbidity and mortality in older adults (aged> 60 years). Efforts to develop a …
cause of morbidity and mortality in older adults (aged> 60 years). Efforts to develop a …
[HTML][HTML] Efficacy and safety of an Ad26. RSV. preF–RSV preF protein vaccine in older adults
AR Falsey, K Williams, E Gymnopoulou… - … England Journal of …, 2023 - Mass Medical Soc
Background Respiratory syncytial virus (RSV) can cause serious lower respiratory tract
disease in older adults, but no licensed RSV vaccine currently exists. An adenovirus …
disease in older adults, but no licensed RSV vaccine currently exists. An adenovirus …
[HTML][HTML] Safety and immunogenicity of ChAdOx1 nCoV-19 vaccine administered in a prime-boost regimen in young and old adults (COV002): a single-blind …
MN Ramasamy, AM Minassian, KJ Ewer, AL Flaxman… - The Lancet, 2020 - thelancet.com
Background Older adults (aged≥ 70 years) are at increased risk of severe disease and
death if they develop COVID-19 and are therefore a priority for immunisation should an …
death if they develop COVID-19 and are therefore a priority for immunisation should an …
[PDF][PDF] Background document on the Janssen Ad26. COV2. S (COVID-19) vaccine: background document to the WHO Interim recommendations for use of Ad26. COV2 …
World Health Organization - 2021 - apps.who.int
Background This background document was prepared by the Strategic Advisory Group of
Experts (SAGE) on Immunization Working Group on COVID-19 Vaccines to inform the …
Experts (SAGE) on Immunization Working Group on COVID-19 Vaccines to inform the …
[HTML][HTML] Phase 1/2 trial of SARS-CoV-2 vaccine ChAdOx1 nCoV-19 with a booster dose induces multifunctional antibody responses
More than 190 vaccines are currently in development to prevent infection by the novel
severe acute respiratory syndrome coronavirus 2. Animal studies suggest that while …
severe acute respiratory syndrome coronavirus 2. Animal studies suggest that while …
Safety and efficacy of single-dose Ad26. COV2. S vaccine against Covid-19
J Sadoff, G Gray, A Vandebosch… - … England Journal of …, 2021 - Mass Medical Soc
Abstract Background The Ad26. COV2. S vaccine is a recombinant, replication-incompetent
human adenovirus type 26 vector encoding full-length severe acute respiratory syndrome …
human adenovirus type 26 vector encoding full-length severe acute respiratory syndrome …
Interim results of a phase 1–2a trial of Ad26. COV2. S Covid-19 vaccine
J Sadoff, M Le Gars, G Shukarev… - … England Journal of …, 2021 - Mass Medical Soc
Background Efficacious vaccines are urgently needed to contain the ongoing coronavirus
disease 2019 (Covid-19) pandemic of infection with severe acute respiratory syndrome …
disease 2019 (Covid-19) pandemic of infection with severe acute respiratory syndrome …
[HTML][HTML] Learning from the past: development of safe and effective COVID-19 vaccines
The rapid spread of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has
elicited an equally rapid response aiming to develop a COVID-19 vaccine. These efforts are …
elicited an equally rapid response aiming to develop a COVID-19 vaccine. These efforts are …
Safety and immunogenicity of a respiratory syncytial virus prefusion F (RSVPreF3) candidate vaccine in older adults: phase 1/2 randomized clinical trial
I Leroux-Roels, MG Davis, K Steenackers… - The Journal of …, 2023 - academic.oup.com
Background The aim of this study was to investigate safety and immunogenicity of vaccine
formulations against respiratory syncytial virus (RSV) containing the stabilized prefusion …
formulations against respiratory syncytial virus (RSV) containing the stabilized prefusion …