Mesenchymal stem/stromal cells as a valuable source for the treatment of immune-mediated disorders
A Markov, L Thangavelu, S Aravindhan… - Stem cell research & …, 2021 - Springer
Over recent years, mesenchymal stem/stromal cells (MSCs) and their potential biomedical
applications have received much attention from the global scientific community in an …
applications have received much attention from the global scientific community in an …
The role of Interleukin 1 receptor antagonist in mesenchymal stem cell‐based tissue repair and regeneration
CR Harrell, BS Markovic, C Fellabaum… - Biofactors, 2020 - Wiley Online Library
Abstract Interleukin (IL)‐1 receptor antagonist (IL‐1Ra), a naturally occurring antagonist of IL‐
1α/IL‐1β signaling pathways, has been attributed to the immunosuppressive effects of …
1α/IL‐1β signaling pathways, has been attributed to the immunosuppressive effects of …
Potential application of mesenchymal stem cells and their exosomes in lung injury: an emerging therapeutic option for COVID-19 patients
S Al-Khawaga, EM Abdelalim - Stem cell research & therapy, 2020 - Springer
The COVID-19 pandemic has negatively impacted the global public health and the
international economy; therefore, there is an urgent need for an effective therapy to treat …
international economy; therefore, there is an urgent need for an effective therapy to treat …
Role of mesenchymal stem cells and their paracrine mediators in macrophage polarization: an approach to reduce inflammation in osteoarthritis
SS Kuppa, HK Kim, JY Kang, SC Lee… - International Journal of …, 2022 - mdpi.com
Osteoarthritis (OA) is a low-grade inflammatory disorder of the joints that causes
deterioration of the cartilage, bone remodeling, formation of osteophytes, meniscal damage …
deterioration of the cartilage, bone remodeling, formation of osteophytes, meniscal damage …
Evaluation of the therapeutic potential of mesenchymal stem cells (MSCs) in preclinical models of autoimmune diseases
RK Shandil, S Dhup, S Narayanan - Stem cells international, 2022 - Wiley Online Library
Autoimmune diseases, chronic in nature, are generally hard to alleviate. Present long‐term
treatments with available drugs such as steroids, immune‐suppressive drugs, or antibodies …
treatments with available drugs such as steroids, immune‐suppressive drugs, or antibodies …
Mechanisms behind the immunoregulatory dialogue between mesenchymal stem cells and Th17 cells
C Terraza-Aguirre, M Campos-Mora, R Elizondo-Vega… - Cells, 2020 - mdpi.com
Mesenchymal stem cells (MSCs) exhibit potent immunoregulatory abilities by interacting
with cells of the adaptive and innate immune system. In vitro, MSCs inhibit the differentiation …
with cells of the adaptive and innate immune system. In vitro, MSCs inhibit the differentiation …
[HTML][HTML] Combination therapy of mesenchymal stromal cells and interleukin-4 attenuates rheumatoid arthritis in a collagen-induced murine model
Rheumatoid arthritis (RA) is a disease of the joints that causes decreased quality of life.
Mesenchymal stromal cells (MSCs) have immunosuppressive properties, with possible use …
Mesenchymal stromal cells (MSCs) have immunosuppressive properties, with possible use …
Impact of type 2 diabetes mellitus on the immunoregulatory characteristics of adipose tissue-derived mesenchymal stem cells
N Abu-Shahba, M Mahmoud, AM El-Erian… - The international journal …, 2021 - Elsevier
Background Type 2 diabetes mellitus (T2DM) is a chronic metabolic disorder associated
with several complications. Adipose tissue-derived mesenchymal stem cells (AT-MSCs) …
with several complications. Adipose tissue-derived mesenchymal stem cells (AT-MSCs) …
Mesenchymal stromal cell based therapies for the treatment of immune disorders: recent milestones and future challenges
A Gonzalez-Pujana, M Igartua… - Expert opinion on …, 2020 - Taylor & Francis
ABSTRACT Introduction: Mesenchymal stromal cells (MSCs) present unique
immunomodulatory properties that make them promising candidates for the treatment of …
immunomodulatory properties that make them promising candidates for the treatment of …
Mesenchymal stem cells suppressed skin and lung inflammation and fibrosis in topoisomerase I-induced systemic sclerosis associated with lung disease mouse …
N Ganesan, YD Chang, SC Hung, JL Lan… - Cell and Tissue …, 2023 - Springer
Systemic sclerosis associated with lung interstitial lung disease (SSc-ILD) is the most
common cause of death among patients with SSc. Mesenchymal stem cell (MSCs) …
common cause of death among patients with SSc. Mesenchymal stem cell (MSCs) …