[HTML][HTML] Cell-binding IgM in CSF is distinctive of multiple sclerosis and targets the iron transporter SCARA5

I Callegari, J Oechtering, M Schneider, S Perriot… - Brain, 2024 - ncbi.nlm.nih.gov
Intrathecal IgM production in multiple sclerosis is associated with a worse disease course.
To investigate pathogenic relevance of autoreactive IgM in multiple sclerosis, CSF from two …

Complement activation is associated with disease severity in multiple sclerosis

J Oechtering, K Stein, SA Schaedelin… - Neurology …, 2024 - AAN Enterprises
Background and Objectives Histopathologic studies have identified immunoglobulin (Ig)
deposition and complement activation as contributors of CNS tissue damage in multiple …

[HTML][HTML] Hallmarks of spinal cord pathology in multiple sclerosis

D Kreiter, AA Postma, R Hupperts, O Gerlach - Journal of the neurological …, 2023 - Elsevier
A disparity exists between spinal cord and brain involvement in multiple sclerosis (MS), each
independently contributing to disability. Underlying differences between brain and cord are …

Oligoclonal M bands unveil occult inflammation in multiple sclerosis

B Casanova, J Castillo, C Quintanilla-Bordás… - Multiple Sclerosis and …, 2022 - Elsevier
Introduction Recent works demonstrate that patients with multiple sclerosis (pwMS) and
oligoclonal M bands (OCMB) in cerebrospinal fluid (CSF) are at higher risk of conversion to …

Basic CSF parameters and MRZ reaction help in differentiating MOG antibody-associated autoimmune disease versus multiple sclerosis

B Vlad, I Reichen, S Neidhart, M Hilty… - Frontiers in …, 2023 - frontiersin.org
Background Myelin oligodendrocyte glycoprotein antibody-associated autoimmune disease
(MOGAD) is a rare monophasic or relapsing inflammatory demyelinating disease of the …

Oligoclonal M bands and cervical spinal cord lesions predict early secondary progressive multiple sclerosis

C Alcalá Vicente, L Lacruz, F Gascón… - Frontiers in …, 2022 - frontiersin.org
Objective To determine baseline cerebrospinal fluid and magnetic resonance imaging (MRI)
variables at the onset of a clinically isolated syndrome (CIS) suggestive of multiple sclerosis …

Predictive Potential of Serum and Cerebrospinal Fluid Biomarkers for Disease Activity in Treated Multiple Sclerosis Patients.

J Tortosa-Carreres, L Cubas-Núñez… - Multiple Sclerosis and …, 2024 - Elsevier
Background: Our objective was to explore various biomarkers for predicting suboptimal
responses to disease-modifying treatments (DMTs) in patients with MS (pwMS). Methods …

Is it cost-effective to request IgM oligoclonal bands against lipids in daily practice as a biomarker for poor prognosis in multiple sclerosis?

SR García, J Castillo-Villalba, RG Rubio… - Multiple Sclerosis and …, 2023 - Elsevier
Background various prognostic factors of multiple sclerosis have been identified, including
demographic, clinical, radiological, and laboratory factors. The aim was to analyze whether …

Utilidad pronóstica de las bandas oligoclonales de tipo IgM frente a lípidos en la esclerosis múltiple

S Ribes García - 2023 - riucv.ucv.es
Las bandas oligoclonales (BOC) de tipo IgM en el líquido cefalorraquídeo (LCR) se han
identificado como un marcador de peor pronóstico en la esclerosis múltiple (EM). El objetivo …

[PDF][PDF] Research@ Department of Neurology

J Asking - 2022 - neurologie.insel.ch
3. Herrera CG† & Girard F†, Bilella A, Gent, TC, Roccaro-Waldmeyer DM, Adamantidis A,
and Celio, MR Neurons in the Nucleus papilio contribute to the control of eye movements …