Understanding the hepatitis C virus life cycle paves the way for highly effective therapies
TKH Scheel, CM Rice - Nature medicine, 2013 - nature.com
More than two decades of intense research has provided a detailed understanding of
hepatitis C virus (HCV), which chronically infects 2% of the world's population. This effort has …
hepatitis C virus (HCV), which chronically infects 2% of the world's population. This effort has …
The ins and outs of hepatitis C virus entry and assembly
BD Lindenbach, CM Rice - Nature Reviews Microbiology, 2013 - nature.com
Hepatitis C virus, a major human pathogen, produces infectious virus particles with several
unique features, such as an ability to interact with serum lipoproteins, a dizzyingly …
unique features, such as an ability to interact with serum lipoproteins, a dizzyingly …
[HTML][HTML] Virology and cell biology of the hepatitis C virus life cycle–An update
J Dubuisson, FL Cosset - Journal of hepatology, 2014 - Elsevier
Hepatitis C virus (HCV) is an important human pathogen that causes hepatitis, liver cirrhosis
and hepatocellular carcinoma. It imposes a serious problem to public health in the world as …
and hepatocellular carcinoma. It imposes a serious problem to public health in the world as …
Ligand density on nanoparticles: A parameter with critical impact on nanomedicine
Nanoparticles modified with ligands for specific targeting towards receptors expressed on
the surface of target cells are discussed in literature towards improved delivery strategies. In …
the surface of target cells are discussed in literature towards improved delivery strategies. In …
Ultrastructural analysis of hepatitis C virus particles
MT Catanese, K Uryu, M Kopp… - Proceedings of the …, 2013 - National Acad Sciences
Hepatitis C virus (HCV) is a major cause of chronic liver disease, with an estimated 170
million people infected worldwide. Low yields, poor stability, and inefficient binding to …
million people infected worldwide. Low yields, poor stability, and inefficient binding to …
[HTML][HTML] Multifaceted roles for lipids in viral infection
Viruses have evolved complex and dynamic interactions with their host cell. In recent years
we have gained insight into the expanding roles for host lipids in the virus life cycle. In …
we have gained insight into the expanding roles for host lipids in the virus life cycle. In …
Assembly of infectious hepatitis C virus particles
A hallmark of the hepatitis C virus (HCV) replication cycle is its tight link with host cell lipid
synthesis. This is best illustrated by the peculiar pathway used for the assembly of infectious …
synthesis. This is best illustrated by the peculiar pathway used for the assembly of infectious …
[PDF][PDF] Hepatitis C virus RNA replication and assembly: living on the fat of the land
Hepatitis C virus (HCV) is a major global health burden accounting for around 170 million
chronic infections worldwide. Although highly potent direct-acting antiviral drugs to treat …
chronic infections worldwide. Although highly potent direct-acting antiviral drugs to treat …
[HTML][HTML] The role of host cholesterol during flavivirus infection
JF Osuna-Ramos, JM Reyes-Ruiz… - Frontiers in cellular and …, 2018 - frontiersin.org
In recent years the emergence and resurgence of arboviruses have generated a global
health alert. Among arboviruses, Dengue (DENV), Zika (ZIKV), Yellow Fever (YFV), and …
health alert. Among arboviruses, Dengue (DENV), Zika (ZIKV), Yellow Fever (YFV), and …
[HTML][HTML] Hepatitis C virus: virology and life cycle
CW Kim, KM Chang - Clinical and molecular hepatology, 2013 - ncbi.nlm.nih.gov
Hepatitis C virus (HCV) is a positive sense, single-stranded RNA virus in the Flaviviridae
family. It causes acute hepatitis with a high propensity for chronic infection. Chronic HCV …
family. It causes acute hepatitis with a high propensity for chronic infection. Chronic HCV …