Advances of the small molecule drugs regulating fibroblast-like synovial proliferation for rheumatoid arthritis

Y Tong, X Li, Q Deng, J Shi, Y Feng… - Frontiers in Pharmacology, 2023 - frontiersin.org
Rheumatoid arthritis (RA) is a type of chronic autoimmune and inflammatory disease. In the
pathological process of RA, the alteration of fibroblast-like synoviocyte (FLS) and its related …

Therapeutic potential of Coptis chinensis for arthritis with underlying mechanisms

M Li, F Tian, J Guo, X Li, L Ma, M Jiang… - Frontiers in …, 2023 - frontiersin.org
Arthritis is a common degenerative disease of joints, which has become a public health
problem affecting human health, but its pathogenesis is complex and cannot be eradicated …

Therapeutic effects of shikonin on adjuvant-induced arthritis in rats and cellular inflammation, migration and invasion of rheumatoid fibroblast-like synoviocytes via …

F Liu, M Wang, M Liu, T Li, X Wang, F Jiang, X Wu… - Phytomedicine, 2023 - Elsevier
Background Shikonin (SKN), the main bioactive component isolated from Lithospermum
erythrorhizon Sieb et Zucc, has multiple activities including anti-rheumatic effect, but its …

Wnt/β-catenin signaling pathway promotes abnormal activation of fibroblast-like synoviocytes and angiogenesis in rheumatoid arthritis and the intervention of Er Miao …

S Chen, J Wang, J Wang, X Jia, Z Xuan, Z Cheng… - Phytomedicine, 2023 - Elsevier
Abstract Background Er Miao San (EMS) is an important herbal formula and a representative
prescription for the treatment of the downwards flow of damp-heat syndrome. Clinical …

Fullerenol inhibits tendinopathy by alleviating inflammation

X Jiao, Z Wang, Y Li, T Wang, C Xu, X Zhou… - … in Bioengineering and …, 2023 - frontiersin.org
Tendinopathy is a common disease in orthopaedics, seriously affecting tendon functions.
However, the effects of non-surgical treatment on tendinopathy are not satisfactory and …

Umbelliferon: A review of its pharmacology, toxicity and pharmacokinetics

Z Lin, X Cheng, H Zheng - Inflammopharmacology, 2023 - Springer
Coumarin, a plant secondary metabolite, has various pharmacological activities, including
antioxidant stress and anti-inflammatory effects. Umbelliferone, a common coumarin …

Ferroptosis: a new strategy for Chinese herbal medicine treatment of diabetic nephropathy

M Wei, X Liu, Z Tan, X Tian, M Li, J Wei - Frontiers in Endocrinology, 2023 - frontiersin.org
Diabetic nephropathy (DN) is a serious microvascular complication of diabetes. It has
become a leading cause of death in patients with diabetes and end-stage renal disease …

Non-coding RNAs involved in fibroblast-like synoviocyte functioning in arthritis rheumatoid: From pathogenesis to therapy

Y Peng, M Zhang, J Hu - Cytokine, 2024 - Elsevier
Rheumatoid arthritis (RA) is a polygenic autoimmune disorder with an uncertain etiology,
primarily impacting the joints. Moreover, the disease may manifest beyond articular …

[PDF][PDF] Development of High-performance Thin-layer Chromatography (HPTLC) Method for Quality Control of Actinidiae Fructus Vermicultus

KH Lee, G Park, S Lee, YG Lee, M Choi, R Lee… - Natural Product …, 2023 - e-nps.or.kr
In this study, we have successfully established a high-performance thin-layer
chromatography (HPTLC) method for the quality assessment of Actinidiae Fructus …