Blunted blades: new CRISPR-derived technologies to dissect microbial multi-drug resistance and biofilm formation
C Gager, AL Flores-Mireles - Msphere, 2024 - Am Soc Microbiol
The spread of multi-drug-resistant (MDR) pathogens has rapidly outpaced the development
of effective treatments. Diverse resistance mechanisms further limit the effectiveness of our …
of effective treatments. Diverse resistance mechanisms further limit the effectiveness of our …
[HTML][HTML] Type I CRISPR-Cas-mediated microbial gene editing and regulation
There are six major types of CRISPR-Cas systems that provide adaptive immunity in
bacteria and archaea against invasive genetic elements. The discovery of CRISPR-Cas …
bacteria and archaea against invasive genetic elements. The discovery of CRISPR-Cas …
Activation of CzcS/CzcR during zinc excess regulates copper tolerance and pyochelin biosynthesis of Pseudomonas aeruginosa
Zinc is an important transition metal that is essential for numerous physiological processes
while excessive zinc is cytotoxic. Pseudomonas aeruginosa is a ubiquitous opportunistic …
while excessive zinc is cytotoxic. Pseudomonas aeruginosa is a ubiquitous opportunistic …
Antibiotic influx and efflux in Pseudomonas aeruginosa: Regulation and therapeutic implications
W Wu, J Huang, Z Xu - Microbial Biotechnology, 2024 - Wiley Online Library
Pseudomonas aeruginosa is a notorious multidrug‐resistant pathogen that poses a serious
and growing threat to the worldwide public health. The expression of resistance …
and growing threat to the worldwide public health. The expression of resistance …
[HTML][HTML] Antimicrobial Resistance (AMR) management using CRISPR-Cas based genome editing
D Sen, P Mukhopadhyay - Gene and Genome Editing, 2024 - Elsevier
Antimicrobial resistance is a serious threat to the human population and might be
responsible for the emergence as well as re-emergence of various infectious diseases. The …
responsible for the emergence as well as re-emergence of various infectious diseases. The …
[PDF][PDF] Gene and Genome Editing
D Sen, P Mukhopadhyay - researchgate.net
Antimicrobial resistance is a serious threat to the human population and might be
responsible for the emergence as well as re-emergence of various infectious diseases. The …
responsible for the emergence as well as re-emergence of various infectious diseases. The …