Sex steroids are major promoters of the growth of breast and prostate cancers. This Review
by Poutanen et al. describes the development of treatments for these cancer types that act to …

It is known that estrogen stimulates growth and inhibits apoptosis through estrogen receptor
(ER)-mediated mechanisms in many cancer cell types. Interestingly, there is strong evidence …

Abstract Background Prostate cancer (PCa) is a leading cause of cancer-related death in
males worldwide. Exacerbated inflammation and angiogenesis have been largely …

Prostate cancer (PC) remains a widespread malignancy in men. Since the
androgen/androgen receptor (AR) axis is associated with the pathogenesis of prostate …

The estrogen signaling pathway has been reported to modulate prostate cancer (PCa)
progression through the activity of estrogen receptors α and β (ERα and ERβ). Given that …

Prostate cancer is initially dependent on the androgen, gradually evolves into an androgen-
independent form of the disease, also known as castration-resistant prostate cancer …

Estrogens are hormones that have been extensively presented in many types of cancer such
as breast, uterus, colorectal, prostate, and others, due to dynamically integrated signaling …

Androgens and estrogens, working together, promote prostate cancer (PRCA) initiation and
progression, with androgens acting via androgen receptor (AR) and estrogens acting …

Understanding the molecular mechanisms underlying prostate cancer (PCa) progression
towards its most aggressive, castration-resistant (CRPC) stage is urgently needed to …

Castration-resistant prostate cancer, or CRPC, is an aggressive stage of prostate cancer
(PCa) in which PCa cells invade nearby or other parts of the body. When a patient with PCa …