Hypertension, diabetes, atherosclerosis and NASH: cause or consequence?

A Lonardo, F Nascimbeni, A Mantovani, G Targher - Journal of hepatology, 2018 - Elsevier
Non-alcoholic fatty liver disease (NAFLD) has become one of the most common forms of
chronic liver disease worldwide and its prevalence is expected to continue rising. NAFLD …

DOCA-salt hypertension: an update

T Basting, E Lazartigues - Current hypertension reports, 2017 - Springer
Hypertension is a multifaceted disease that is involved in∼ 40% of cardiovascular
mortalities and is the result of both genetic and environmental factors. Because of its …

Pathophysiology of hypertensive heart disease: beyond left ventricular hypertrophy

CC Nwabuo, RS Vasan - Current hypertension reports, 2020 - Springer
Abstract Purpose of Review Given that the life expectancy and the burden of hypertension
are projected to increase over the next decade, hypertensive heart disease (HHD) may be …

[HTML][HTML] Myocardial fibrosis

T Espeland, IG Lunde, BH Amundsen… - Tidsskrift for Den …, 2018 - tidsskriftet.no
BACKGROUND Myocardial fibrosis arises secondary to cardiac stress or damage. This
review article presents fundamental aspects of myocardial fibrosis. METHOD METHOD We …

Association of arsenic exposure with cardiac geometry and left ventricular function in young adults: evidence from the Strong Heart Family Study

G Pichler, M Grau-Perez, M Tellez-Plaza… - Circulation …, 2019 - Am Heart Assoc
Background: Arsenic exposure has been related to numerous adverse cardiovascular
outcomes. The aim of this study was to investigate the cross-sectional and prospective …

Preclinical rodent models of cardiac fibrosis

Y Wang, M Wang, CS Samuel… - British Journal of …, 2022 - Wiley Online Library
Cardiac fibrosis (scarring), characterised by an increased deposition of extracellular matrix
(ECM) proteins, is a hallmark of most types of cardiovascular disease and plays an essential …

The effect of blood flow-restricted low resistance training on microvascular circulation of myocardium in spontaneously hypertensive rats

Z Tan, Y Zhao, Y Zheng, Y Pan - Frontiers in Physiology, 2022 - frontiersin.org
Objective: The purpose of this study was to explore the effect of blood flow-restricted low
resistance training on microvascular rarefaction in the myocardium of spontaneously …

Changes in the number of mast cells, expression of fibroblast growth factor-2 and extent of interstitial fibrosis in established and advanced hypertensive heart disease

G Kotov, B Landzhov, N Stamenov, S Stanchev… - Annals of Anatomy …, 2020 - Elsevier
Introduction An increasing number of studies have shed light on the role of cardiac mast
cells in the pathogenesis of hypertension-induced myocardial remodeling. Mast cells …

Research on the mechanism and prevention of hypertension caused by apatinib through the RhoA/ROCK signaling pathway in a mouse model of gastric cancer

W Wang, C Li, C Zhuang, H Zhang, Q Wang… - Frontiers in …, 2022 - frontiersin.org
Hypertension is one of the main adverse effects of antiangiogenic tumor drugs and thus
limits their application. The mechanism of hypertension caused by tyrosine kinase inhibitors …

ESCRT-III Component CHMP4C Attenuates Cardiac Hypertrophy by Targeting the Endo-Lysosomal Degradation of EGFR

A Liu, H Xie, F Tian, P Bai, H Weng, Y Liu, W Liu… - …, 2023 - Am Heart Assoc
BACKGROUND: Cardiac hypertrophy and subsequent heart failure impose a considerable
burden on public health worldwide. Impaired protein degradation, especially endo-lysosome …