Advances in the bacterial organelles for CO2 fixation

LN Liu - Trends in Microbiology, 2022 - cell.com
Carboxysomes are a family of bacterial microcompartments (BMCs), present in all
cyanobacteria and some proteobacteria, which encapsulate the primary CO 2-fixing …

[HTML][HTML] Engineering α-carboxysomes into plant chloroplasts to support autotrophic photosynthesis

T Chen, M Hojka, P Davey, Y Sun, GF Dykes… - Nature …, 2023 - nature.com
The growth in world population, climate change, and resource scarcity necessitate a
sustainable increase in crop productivity. Photosynthesis in major crops is limited by the …

[HTML][HTML] Intrinsically disordered CsoS2 acts as a general molecular thread for α-carboxysome shell assembly

T Ni, Q Jiang, PC Ng, J Shen, H Dou, Y Zhu… - Nature …, 2023 - nature.com
Carboxysomes are a paradigm of self-assembling proteinaceous organelles found in nature,
offering compartmentalisation of enzymes and pathways to enhance carbon fixation. In α …

[HTML][HTML] Structure and assembly of cargo Rubisco in two native α-carboxysomes

T Ni, Y Sun, W Burn, MMJ Al-Hazeem, Y Zhu… - Nature …, 2022 - nature.com
Carboxysomes are a family of bacterial microcompartments in cyanobacteria and
chemoautotrophs. They encapsulate Ribulose 1, 5-bisphosphate carboxylase/oxygenase …

Incorporation of functional Rubisco activases into engineered carboxysomes to enhance carbon fixation

T Chen, Y Fang, Q Jiang, GF Dykes, Y Lin… - ACS synthetic …, 2021 - ACS Publications
The carboxysome is a versatile paradigm of prokaryotic organelles and is a proteinaceous
self-assembling microcompartment that plays essential roles in carbon fixation in all …

Decoding the absolute stoichiometric composition and structural plasticity of α-carboxysomes

Y Sun, VM Harman, JR Johnson, PJ Brownridge… - MBio, 2022 - Am Soc Microbiol
Carboxysomes are anabolic bacterial microcompartments that play an essential role in
carbon fixation in cyanobacteria and some chemoautotrophs. This self-assembling …

Probing the internal pH and permeability of a carboxysome shell

J Huang, Q Jiang, M Yang, GF Dykes… - …, 2022 - ACS Publications
The carboxysome is a protein-based nanoscale organelle in cyanobacteria and many
proteobacteria, which encapsulates the key CO2-fixing enzymes ribulose-1, 5-bisphosphate …

[HTML][HTML] Synthetic engineering of a new biocatalyst encapsulating [NiFe]-hydrogenases for enhanced hydrogen production

Q Jiang, T Li, J Yang, CM Aitchison, J Huang… - Journal of Materials …, 2023 - pubs.rsc.org
Hydrogenases are microbial metalloenzymes capable of catalyzing the reversible
interconversion between molecular hydrogen and protons with high efficiency, and have …

Computational modeling and evolutionary implications of biochemical reactions in bacterial microcompartments

CA Huffine, LC Wheeler, B Wing… - Current Opinion in …, 2022 - Elsevier
Highlights•Computational modeling of BMCs enlightens experimentally hard-to-measure
features.•Significant exploration remains of catabolic BMC capabilities.•Oxygen sensitivity is …

Kinetic growth of multicomponent microcompartment shells

C Waltmann, NW Kennedy, CE Mills, EW Roth… - ACS …, 2023 - ACS Publications
An important goal of systems and synthetic biology is to produce high value chemical
species in large quantities. Microcompartments, which are protein nanoshells encapsulating …