Therapeutic properties of honey for the management of wounds; is there a role in the armamentarium of diabetic foot ulcer treatment? Results from in vitro and in vivo …

IA Anastasiou, I Eleftheriadou… - … Journal of Lower …, 2021 - journals.sagepub.com
Diabetic foot ulcers are one of the most dreadful complications of diabetes mellitus and
efforts to accelerate diabetic wound healing are of paramount importance to prevent ulcer …

Ferritin and iron supplements in gestational diabetes mellitus: less or more?

T Li, J Zhang, P Li - European Journal of Nutrition, 2024 - Springer
Iron metabolism has been found to be closely related to gestational diabetes mellitus (GDM).
Excessive ferritin levels were shown to be related to an increased risk of GDM because of …

[HTML][HTML] The coffee diterpene, kahweol, ameliorates pancreatic β-cell function in streptozotocin (STZ)-treated rat INS-1 cells through NF-kB and p-AKT/Bcl-2 pathways

W El-Huneidi, S Anjum, K Bajbouj, E Abu-Gharbieh… - Molecules, 2021 - mdpi.com
Kahweol is a diterpene molecule found in coffee that exhibits a wide range of biological
activity, including anti-inflammatory and anticancer properties. However, the impact of …

[HTML][HTML] Vitamin D alleviates type 2 diabetes Mellitus by mitigating oxidative stress-Induced pancreatic β-Cell impairment

J Liu, Y Zhang, D Shi, C He… - Experimental and Clinical …, 2023 - thieme-connect.com
Objective Type 2 diabetes mellitus (T2DM) is a common metabolic disorder with rising
incidence worldwide. This study explored the anti-T2DM role of vitamin D, thereby providing …

Low concentrations of bisphenol A promote the activation of the mitochondrial apoptotic pathway on Beta‐TC‐6 cells via the generation of intracellular reactive oxygen …

IA Anastasiou, I Eleftheriadou… - … of Biochemical and …, 2022 - Wiley Online Library
Τhe natural history of type 2 diabetes mellitus is characterized by a progressive loss of
pancreatic beta cell function and insulin resistance. Bisphenol A (BPA) is an endocrine …

GDF15 plays a critical role in insulin secretion in INS-1 cells and human pancreatic islets

MG Mohammad, R Saeed… - Experimental …, 2023 - journals.sagepub.com
Mounting evidence points to a link between growth differentiation factor-15 (GDF15)
expression and the onset and progression of diabetes mellitus. However, the exact role of …

[HTML][HTML] Angiotensin-converting enzyme 2 improves hepatic insulin resistance by regulating GABAergic signaling in the liver

Q Chen, Y Gao, F Yang, H Deng, Y Wang… - Journal of Biological …, 2022 - ASBMB
The angiotensin-converting enzyme 2 (ACE2)/angiotensin 1–7/MAS axis and the gamma-
aminobutyric acid (GABA) ergic signaling system have both been shown to have the dual …

[HTML][HTML] Carnosic acid protects INS-1 β-cells against streptozotocin-induced damage by inhibiting apoptosis and improving insulin secretion and glucose uptake

W El-Huneidi, S Anjum, MA Saleh, Y Bustanji… - Molecules, 2022 - mdpi.com
Carnosic acid (CA), a natural polyphenolic diterpene derived from Rosmarinus officinalis,
has been proven to possess a broad spectrum of medicinal properties. Nevertheless, no …

[HTML][HTML] Knowledge domain and emerging trends in beta‐cell research: A bibliometric and knowledge‐map analysis

Y Luo, T Wang, Z Chen, G Zhang - Frontiers in Endocrinology, 2023 - frontiersin.org
Background Up to now, the physiology, pathology, and recovery of beta-cells have been
intensively studied and made great progress, and these are of major significance for the …

[HTML][HTML] The effects of beta-cell mass and function, intercellular coupling, and islet synchrony on dynamics

M Saadati, Y Jamali - Scientific Reports, 2021 - nature.com
Abstract Type 2 diabetes (T2D) is a challenging metabolic disorder characterized by a
substantial loss of β-cell mass and alteration of β-cell function in the islets of Langerhans …