Effective revascularization of the patient with peripheral artery disease is about more than
the procedure. The approach to the patient with symptom-limiting intermittent claudication or …

with the matrix and with the periodicity of negative charges on collagen. Crystals initially
form octacalcium phosphate [Ca8H2 (PO4) 6· 5H2O], which reorganizes and seeds epitaxial …

Guideline Summary Chronic limb-threatening ischemia (CLTI) is associated with mortality,
amputation, and impaired quality of life. These Global Vascular Guidelines (GVG) are …

Bone never forms without vascular interactions. This simple statement of fact does not
adequately reflect the physiological and pharmacological implications of the relationship …

Lower extremity atherosclerotic peripheral artery disease (PAD) has a very high prevalence
in most nations and in the United States. 1–8 Lower extremity PAD is now known to be …

Peripheral arterial disease (PAD) is a global health issue that is becoming more prevalent in
an aging world population. Diabetes mellitus and chronic kidney disease are also on the …

Arterial biomineralization processes have been afflicting humans for 5 millennia, as realized
in 2003 via the computed tomographic imaging of Otzi, the intriguing “ice mummy” …

Objectives: The purpose of this study was to determine whether ancient Egyptians had
atherosclerosis. Background: The worldwide burden of atherosclerotic disease continues to …

Purpose: To evaluate the safety and feasibility of treating calcified infrapopliteal stenoses
using an intravascular lithotripsy (IVL) system. Methods: The Disrupt BTK study was a …

Background: In pseudoxanthoma elasticum (PXE), low pyrophosphate levels may cause
ectopic mineralization, leading to skin changes, visual impairment, and peripheral arterial …