Inflammation is increasingly implicated as a risk factor for dementia, stroke, and small vessel
disease (SVD). However, the underlying mechanisms and causative pathways remain …

Cerebral small vessel disease (cSVD) has a crucial role in lacunar stroke and brain
hemorrhages and is a leading cause of cognitive decline and functional loss in elderly …

The term cerebral small vessel disease (SVD) describes a range of neuroimaging,
pathological, and associated clinical features. Clinical features range from none, to discrete …

Abstract The 'Vascular Depression'hypothesis posits that cerebrovascular disease may
predispose, precipitate or perpetuate some geriatric depressive syndromes. This hypothesis …

Proinflammatory conditions, including acute and chronic infections, have been associated
with an increased risk of stroke. The risk of stroke is increased by both the acute and chronic …

Cerebral small vessel disease (cSVD) is the most common cause of vascular cognitive
impairment and affects all levels of the brain's vasculature. Features include diverse …

The glymphatic system has recently been shown to clear brain extracellular solutes and
abnormalities in glymphatic clearance system may contribute to both initiation and …

The term cerebral small vessel disease (SVD) refers to a group of pathologic processes with
various etiologies that affect small arteries, arterioles, venules, and capillaries of the brain …

Objective: The relation between inflammation and brain MRI findings in the elderly remains
poorly known. We investigated the association of circulating interleukin-6 (IL-6) and C …

Downregulation of IL-6 (interleukin-6) signaling has been proposed as a strategy for
lowering cardiovascular risk. Secondary analyses from CANTOS (Canakinumab Anti …