Background The risk of dementia is higher in women than men. The metabolic
consequences of estrogen decline during menopause accelerate neuropathology in …

Background The vast majority of women with dementia are post-menopausal. Despite
clinical relevance, menopause is underrepresented in rodent models of dementia. Before …

There have been ongoing efforts by federal agencies and scientific communities since the
early 1990s to incorporate sex and/or gender in all aspects of cardiovascular research …

Hypertension is a leading modifiable risk factor for cerebral small vessel disease. Our
laboratory has shown that endothelium-dependent dilation in cerebral parenchymal …

Individuals aged≥ 65 yr will comprise∼ 20% of the global population by 2030.
Cardiovascular disease remains the leading cause of death in the world with age-related …

Background: Alzheimer's disease (AD) is associated with impaired cerebral circulation
which underscores diminished delivery of blood oxygen and nutrients to and throughout the …

Background This study aimed to delineate the association between menopausal-related
symptoms and brain cortical hemodynamics in peri-postmenopause women. Methods Cross …

Menopause is a major endocrinological shift that leads to an increased vulnerability to the
risk factors for cognitive impairment and dementia. This is thought to be due to the loss of …

Hypertension is a leading modifiable risk factor for cerebral small vessel disease. Our
laboratory has shown that endothelium-dependent dilation in cerebral parenchymal …

Cerebral microvascular dysfunction and nitro-oxidative stress are present in patients with
Alzheimer's disease (AD) and may contribute to disease progression and severity. Large …