Traumatic brain injury (TBI) remains one of the leading causes of morbidity and mortality
amongst civilians and military personnel globally. Despite advances in our knowledge of the …

Neuronal and glial cell death and traumatic axonal injury contribute to the overall pathology
of traumatic brain injury (TBI) in both humans and animals. In both head‐injured humans …

The transcription factor NF-E2-related factor 2 (Nrf2) is a central regulator of cellular
antioxidant and detoxification response. The association between Nrf2 activity and iron …

The classical phytoestrogens, so far known, constitute a group of plant-derived compounds
which include mainly isoflavones, lignans, coumestanes, stilbenes and the flavonoids …

Background Secondary damage after spinal cord injury (SCI) is characterized by a cascade
of events including hemorrhage, apoptosis, oxidative stress, and inflammation which …

Autophagy, a bulk degradation of subcellular constituents, is activated in several
neurodegenerative conditions. Beclin 1, a Bcl2 interacting protein, was found to promote …

Physical activity has been considered an important non-medication intervention in
preserving mnemonic processes during aging. However, how aerobic exercise promotes …

The brain-gut axis (BGA) is a significant bidirectional communication pathway between the
brain and gut. Traumatic brain injury (TBI) induced neurotoxicity and neuroinflammation can …

Recent experimental data have shown that hyperbaric oxygen therapy (HBOT) was
associated increased Bcl-2 expression at the injury site that correlated with reduced …

Traumatic brain injury (TBI) signifies a major cause of death and disability. TBI causes
central nervous system (CNS) damage under a variety of mechanisms, including protein …