[HTML][HTML] Extracellular vesicles as personalized medicine

DJ Beetler, DN Di Florio, KA Bruno, T Ikezu… - Molecular aspects of …, 2023 - Elsevier
Extracellular vesicles (EVs) are released from all cells in the body, forming an important
intercellular communication network that contributes to health and disease. The contents of …

[HTML][HTML] Therapeutic strategy of mesenchymal-stem-cell-derived extracellular vesicles as regenerative medicine

Y Matsuzaka, R Yashiro - International Journal of Molecular Sciences, 2022 - mdpi.com
Extracellular vesicles (EVs) are lipid bilayer membrane particles that play critical roles in
intracellular communication through EV-encapsulated informative content, including …

[HTML][HTML] Extracellular vesicles as drug transporters

M Nowak, J Górczyńska, K Kołodzińska… - International Journal of …, 2023 - mdpi.com
Extracellular vesicles (EVs) are lipid bilayer-delimited particles. According to their size and
synthesis pathway, EVs can be classified into exosomes, ectosomes (microvesicles), and …

[HTML][HTML] Adipose-derived mesenchymal stromal cells in basic research and clinical applications

K Czerwiec, M Zawrzykraj, M Deptuła… - International Journal of …, 2023 - mdpi.com
Adipose-derived mesenchymal stromal cells (AD-MSCs) have been extensively studied in
recent years. Their attractiveness is due to the ease of obtaining clinical material (fat tissue …

[HTML][HTML] Stem cell-based therapeutic strategies for premature ovarian insufficiency and infertility: a focus on aging

I Ali, AA Padhiar, T Wang, L He, M Chen, S Wu, Y Zhou… - Cells, 2022 - mdpi.com
Reproductive aging is on the rise globally and inseparable from the entire aging process. An
extreme form of reproductive aging is premature ovarian insufficiency (POI), which to date …

[HTML][HTML] Practical considerations for translating mesenchymal stromal cell-derived extracellular vesicles from bench to bed

PPY Lui, YT Leung - Pharmaceutics, 2022 - mdpi.com
Extracellular vesicles (EVs) derived from mesenchymal stromal cells (MSCs) have shown
potential for the treatment of tendon and ligament injuries. This approach can eliminate the …

[HTML][HTML] Frontier review of the molecular mechanisms and current approaches of stem cell-derived exosomes

LY Chen, TW Kao, CC Chen, N Niaz, HL Lee, YH Chen… - Cells, 2023 - mdpi.com
Exosomes are effective therapeutic vehicles that may transport their substances across cells.
They are shown to possess the capacity to affect cell proliferation, migration, anti-apoptosis …

[HTML][HTML] Tumor-derived small extracellular vesicles involved in breast cancer progression and drug resistance

L Feng, L Guo, Y Tanaka, L Su - International Journal of Molecular …, 2022 - mdpi.com
Breast cancer is one of the most serious and terrifying threats to the health of women.
Recent studies have demonstrated that interaction among cancer cells themselves and …

A vivid outline demonstrating the benefits of exosome-mediated drug delivery in CNS-associated disease environments

R Ray, SG Chowdhury, P Karmakar - Archives of Biochemistry and …, 2024 - Elsevier
The efficacy of drug delivery mechanisms has been improvised with time for different
therapeutic purposes. In most cases, nano-sized delivery systems have been modeled over …

[HTML][HTML] Selective loading and variations in the miRNA profile of extracellular vesicles from endothelial-like cells cultivated under normoxia and hypoxia

AW Robert, BH Marcon, ABB Angulski… - International journal of …, 2022 - mdpi.com
Endothelial-like cells may be obtained from CD133+ mononuclear cells isolated from human
umbilical cord blood (hUCB) and expanded using endothelial-inducing medium (E-CD133 …