[HTML][HTML] The roles and mechanism of m6A RNA methylation regulators in cancer immunity
L Chen, Y He, J Zhu, S Zhao, S Qi, X Chen… - Biomedicine & …, 2023 - Elsevier
Abstract N 6-methyladenosine (m 6 A), the most common internal modification in RNA, can
be regulated by three types of regulators, including methyltransferases (writers) …
be regulated by three types of regulators, including methyltransferases (writers) …
The structure and function of YTHDF epitranscriptomic m6A readers
V Sikorski, S Selberg, M Lalowski, M Karelson… - Trends in …, 2023 - cell.com
Specific RNA sequences modified by a methylated adenosine, N 6-methyladenosine (m 6
A), contribute to the post-transcriptional regulation of gene expression. The quantity of m 6 A …
A), contribute to the post-transcriptional regulation of gene expression. The quantity of m 6 A …
[HTML][HTML] Ythdf2 promotes pulmonary hypertension by suppressing Hmox1-dependent anti-inflammatory and antioxidant function in alveolar macrophages
L Hu, Y Yu, Y Shen, H Huang, D Lin, K Wang, Y Yu… - Redox Biology, 2023 - Elsevier
Pulmonary hypertension (PH) is a devastating disease characterized by irreversible
pulmonary vascular remodeling (PVR) that causes right ventricular failure and death. The …
pulmonary vascular remodeling (PVR) that causes right ventricular failure and death. The …
[HTML][HTML] m6A modification on the fate of colorectal cancer: functions and mechanisms of cell proliferation and tumorigenesis
X Jiang, Z Jin, Y Yang, X Zheng, S Chen… - Frontiers in …, 2023 - frontiersin.org
N6-methyladenosine (m6A) is the most pervasive RNA modification in eukaryotic cells. The
dynamic and reversible m6A modification of RNA plays a critical role in tumor occurrence …
dynamic and reversible m6A modification of RNA plays a critical role in tumor occurrence …
LINC00707 impairs the Natural Killer cell antitumour activity in hepatocellular carcinoma through decreasing YTHDF2 stability
M Wei, L Lu, J Ma, Z Luo, X Tan… - Journal of Cellular and …, 2024 - Wiley Online Library
Hepatocellular carcinoma (HCC) is the fifth most frequently diagnosed cancer and ranks
third in cancer‐related fatalities. The recognized involvement of long noncoding RNAs …
third in cancer‐related fatalities. The recognized involvement of long noncoding RNAs …
m6A‑mediated LINC02038 inhibits colorectal cancer progression via regulation of the FAM172A/PI3K/AKT pathway via competitive binding with miR‑552‑5p
W Liu, Z Zhang, X Luo, K Qian… - International …, 2023 - spandidos-publications.com
Long noncoding RNAs (lncRNAs) are a type of regulatory molecule with potential roles in
the development of several different malignancies. However, the underlying mechanisms of …
the development of several different malignancies. However, the underlying mechanisms of …
The role of m6A Modification in the risk prediction and Notch1 pathway of Alzheimer's disease
Y Qiao, Y Mei, M Xia, D Luo, L Gao - iScience, 2024 - cell.com
Summary N6-methyladenosine (m6A) methylation and abnormal immune responses are
implicated in neurodegenerative diseases, yet their relationship in Alzheimer's Disease (AD) …
implicated in neurodegenerative diseases, yet their relationship in Alzheimer's Disease (AD) …
YTHDF2 negatively correlates with tumor immune infiltration in small cell lung cancer
G Chen, D Ren, Y Wang, H Wang, J Zhang… - Journal of Molecular …, 2023 - Springer
In recent times, RNA modifications have garnered increased attention due to their
involvement in the onset and progression of tumors, with N6-methyladenosine (m6A) …
involvement in the onset and progression of tumors, with N6-methyladenosine (m6A) …
The three YTHDF paralogs and VIRMA are the major tumor drivers among the m6A core genes in a pan-cancer analysis
N6-methyladenosine (m6A) is the most abundant internal modification in mRNAs. Despite
accumulating evidence for the profound impact of m6A on cancer biology, there are …
accumulating evidence for the profound impact of m6A on cancer biology, there are …