Energy homeostasis in the brain is maintained by oxidative metabolism of glucose, primarily
to fulfil the energy demand associated with ionic movements in neurons and astrocytes. In …

The particulate hexokinase activity of rat brain is interconvertible among soluble, particulate,
and latent (also particulate) forms. Changes in the distribution of the enzyme among these …

Glucose and oxygen (O 2) are vital to the brain. Glucose metabolism and mitochondria play
a pivotal role in this process, culminating in the increase of reactive O 2 species. Hexokinase …

The Mammalian Mitochondrial Respiratory Chain provides the vocabulary related to the
mitochondrial respiratory chain in mammalian species. It explores the heterogeneous nature …

Several glycolytic enzymes were observed to have between 40–90% of their activities
associated with the particulate fractions of lysed nerve endings. The enzymes showing high …

The present review focuses on the methodological aspects of glycolytic, tricarboxylic acid
(TCA) cycle, and related enzymes, and on a discussion of how the methodologies can be …

Hexokinase has been purified from pig heart to a specific activity of 80 units/mg. The enzyme
has an s20 of 5.11±0.15 S and a molecular weight of 97000. Dodecylsulphate …

A method has been developed for the rapid large scale isolation of plasma membranes and
intact nuclei from RAJI lymphoid cells utilizing hypotonic lysis of cells after intracellular …

Two methods of preparing a mitochondrial fraction from beef brain cortex are described.
Data are presented on the rate of oxidation of substrates, P/O and respiratory control ratios …

Anyone who has any contact with mental patients, old or young, or their families, or just visits
a mental hospital or school for the retarded, is aware of the tremendous suffering caused by …