Catalytic approaches to chemo-and site-selective transformation of carbohydrates
K Yamatsugu, M Kanai - Chemical Reviews, 2023 - ACS Publications
Carbohydrates are a fundamental unit playing pivotal roles in all the biological processes. It
is thus essential to develop methods for synthesizing, functionalizing, and manipulating …
is thus essential to develop methods for synthesizing, functionalizing, and manipulating …
Recent chemical synthesis of plant polysaccharides
X Wang, G Xiao - Current Opinion in Chemical Biology, 2023 - Elsevier
Here, chemical syntheses of long, branched and complex glycans over 10-mer from plants
are summarized, which highlights amylopectin 20-mer from starch, 17-mer from carthamus …
are summarized, which highlights amylopectin 20-mer from starch, 17-mer from carthamus …
Site-selective C–O bond editing of unprotected saccharides
G Wang, CC Ho, Z Zhou, YJ Hao, J Lv… - Journal of the …, 2023 - ACS Publications
Glucose and its polyhydroxy saccharide analogs are complex molecules that serve as
essential structural components in biomacromolecules, natural products, medicines, and …
essential structural components in biomacromolecules, natural products, medicines, and …
Direct identification of complex glycans via a highly sensitive engineered nanopore
G Yao, Y Tian, W Ke, J Fang, S Ma, T Li… - Journal of the …, 2024 - ACS Publications
The crucial roles that glycans play in biological systems are determined by their structures.
However, the analysis of glycan structures still has numerous bottlenecks due to their …
However, the analysis of glycan structures still has numerous bottlenecks due to their …
Lignocellulosic biomass-based glycoconjugates for diverse biotechnological applications
CER Reis, TS Milessi, MDN Ramos, AK Singh… - Biotechnology …, 2023 - Elsevier
Glycoconjugates are the ubiquitous components of mammalian cells, mainly synthesized by
covalent bonds of carbohydrates to other biomolecules such as proteins and lipids, with a …
covalent bonds of carbohydrates to other biomolecules such as proteins and lipids, with a …
Immune checkpoint therapy-elicited sialylation of IgG antibodies impairs antitumorigenic type I interferon responses in hepatocellular carcinoma
RQ Wu, XM Lao, DP Chen, H Qin, M Mu, WJ Cao… - Immunity, 2023 - cell.com
The reinvigoration of anti-tumor T cells in response to immune checkpoint blockade (ICB)
therapy is well established. Whether and how ICB therapy manipulates antibody-mediated …
therapy is well established. Whether and how ICB therapy manipulates antibody-mediated …
C‐Glycoside Synthesis Enabled by Nickel Catalysis
W Shang, R Shi, D Niu - Chinese Journal of Chemistry, 2023 - Wiley Online Library
Comprehensive Summary C‐Glycosides are critical, naturally occurring products and
medicinal candidates, and extensive efforts have been made to explore efficient approaches …
medicinal candidates, and extensive efforts have been made to explore efficient approaches …
[HTML][HTML] Carriers and antigens: new developments in glycoconjugate vaccines
RMF van der Put, B Metz, RJ Pieters - Vaccines, 2023 - mdpi.com
Glycoconjugate vaccines have proven their worth in the protection and prevention of
infectious diseases. The introduction of the Haemophilus influenzae type b vaccine is the …
infectious diseases. The introduction of the Haemophilus influenzae type b vaccine is the …
Strategies for automated enzymatic glycan synthesis (AEGS)
KP Hussnaetter, P Palm, A Pich, M Franzreb… - Biotechnology …, 2023 - Elsevier
Glycans are the most abundant biopolymers on earth and are constituents of glycoproteins,
glycolipids, and proteoglycans with multiple biological functions. The availability of different …
glycolipids, and proteoglycans with multiple biological functions. The availability of different …
Carrier diversity and chemical ligations in the toolbox for designing tumor-associated carbohydrate antigens (TACAs) as synthetic vaccine candidates
R Roy, L Mousavifar - Chemical Society Reviews, 2023 - pubs.rsc.org
This review highlights the recent development in the use of carriers of increasing simplicities
and versatile chemical ligation processes leading to synthetic vaccine candidates against …
and versatile chemical ligation processes leading to synthetic vaccine candidates against …