Prevention and treatment of monkeypox
Human monkeypox is a zoonotic orthopoxvirus with presentation similar to smallpox.
Monkeypox is transmitted incidentally to humans when they encounter infected animals …
Monkeypox is transmitted incidentally to humans when they encounter infected animals …
[HTML][HTML] Monkeypox: epidemiology, pathogenesis, treatment and prevention
Y Huang, L Mu, W Wang - Signal Transduction and Targeted Therapy, 2022 - nature.com
Monkeypox is a zoonotic disease that was once endemic in west and central Africa caused
by monkeypox virus. However, cases recently have been confirmed in many nonendemic …
by monkeypox virus. However, cases recently have been confirmed in many nonendemic …
An overview of tecovirimat for smallpox treatment and expanded anti-orthopoxvirus applications
AT Russo, DW Grosenbach… - Expert review of anti …, 2021 - Taylor & Francis
ABSTRACT Introduction Tecovirimat (TPOXX®; ST-246) was approved for the treatment of
symptomatic smallpox by the USFDA in July of 2018 and has been stockpiled by the US …
symptomatic smallpox by the USFDA in July of 2018 and has been stockpiled by the US …
Pharmacokinetics and efficacy of a potential smallpox therapeutic, brincidofovir, in a lethal monkeypox virus animal model
CL Hutson, AV Kondas, MR Mauldin, JB Doty… - MSphere, 2021 - Am Soc Microbiol
Smallpox, caused by Variola virus (VARV), was eradicated in 1980; however, VARV
bioterrorist threats still exist, necessitating readily available therapeutics. Current …
bioterrorist threats still exist, necessitating readily available therapeutics. Current …
A review of experimental and natural infections of animals with monkeypox virus between 1958 and 2012
S Parker, RM Buller - Future virology, 2013 - Taylor & Francis
Monkeypox virus (MPXV) was discovered in 1958 during an outbreak in an animal facility in
Copenhagen, Denmark. Since its discovery, MPXV has revealed a propensity to infect and …
Copenhagen, Denmark. Since its discovery, MPXV has revealed a propensity to infect and …
Benefit-risk assessment for brincidofovir for the treatment of smallpox: US Food and Drug Administration's Evaluation
K Chan-Tack, P Harrington, T Bensman, SY Choi… - Antiviral research, 2021 - Elsevier
The development and approval of brincidofovir for the treatment of smallpox, a disease that
was eradicated from the world over 40 years ago, has resulted in the second antiviral …
was eradicated from the world over 40 years ago, has resulted in the second antiviral …
Development of CMX001 (Brincidofovir) for the treatment of serious diseases or conditions caused by dsDNA viruses
DF Florescu, MA Keck - Expert review of anti-infective therapy, 2014 - Taylor & Francis
CMX001 (hexadecyloxypropyl-cidofovir, Brincidofovir) is a broad spectrum, lipid conjugate
of cidofovir that is converted intracellularly into the active antiviral, cidofovir diphosphate …
of cidofovir that is converted intracellularly into the active antiviral, cidofovir diphosphate …
Current insights into diagnosis, prevention strategies, treatment, therapeutic targets, and challenges of monkeypox (Mpox) infections in human populations
In the wake of the emergence and worldwide respread of a viral infection called Monkeypox
(Mpox), there is a serious threat to the health and safety of the global population. This viral …
(Mpox), there is a serious threat to the health and safety of the global population. This viral …
Monkeypox: a review of the 2022 outbreak
EY Lim, J Whitehorn, L Rivett - British Medical Bulletin, 2023 - academic.oup.com
Abstract Introduction In May 2022, the World Health Organisation declared a multi-country
monkeypox outbreak in non-endemic countries following cases reported from 12 member …
monkeypox outbreak in non-endemic countries following cases reported from 12 member …
Monkeypox—what pediatricians need to know
P Zimmermann, N Curtis - The Pediatric Infectious Disease …, 2022 - journals.lww.com
Monkeypox is a zoonotic disease, presenting with fever, lymphadenopathy and vesicular-
pustular skin lesions, that historically has rarely been reported outside the endemic regions …
pustular skin lesions, that historically has rarely been reported outside the endemic regions …