Shikonin and its derivatives, isolated from traditional medicinal plant species of the genus
Lithospermum, Alkanna, Arnebia, Anchusa, Onosma, and Echium belonging to the …

Background Shikonin is one of the major phytochemical components of Lithospermum
erythrorhizon (Purple Cromwell), which is a type of medicinal herb broadly utilized in …

Perilla frutescens essential oil (PEO) has been widely used as a food preservative. This
study aimed to clarify the mechanism of PEO against Aspergillus flavus (A. flavus) at the …

Shikonin and its derivatives are the natural naphthoquinone compounds produced in the
roots of the Boraginaceae family. These red pigments have been used for a long time in …

Abstract Alkannin/shikonin (A/S) and their derivatives are naturally occurring
naphthoquinones majorly found in Boraginaceae family plants. They are integral …

Introduction Secondary metabolites, also called specialized metabolites, are essential in
defense and cell-to-cell communication that play a significant role in pharmacotherapy …

Increasing prevalence of antimicrobial resistance (AMR) has posed a major health concern
worldwide, and the addition of new antimicrobial agents is diminishing due to …

Aspergillus species encompass a variety of infections, ranging from invasive aspergillosis to
allergic conditions, contingent upon the immune status of the host. In this spectrum …

Antimicrobial resistance has been developing fast and incurring a loss of human life, and
there is a need for new antimicrobial agents. Naturally occurring antimicrobial peptides offer …

Aspergillus flavus (A. flavus) is one pathogenic fungus that severely endangers human
health and food safety. In our previous work, paeonol, a natural active compound from …