Advances in sequencing technology

EY Chan - … Research/Fundamental and Molecular Mechanisms of …, 2005 - Elsevier
Faster sequencing methods will undoubtedly lead to faster single nucleotide polymorphism
(SNP) discovery. The Sanger method has served as the cornerstone for genome sequence …

Real-time DNA sequencing from single polymerase molecules

J Eid, A Fehr, J Gray, K Luong, J Lyle, G Otto, P Peluso… - Science, 2009 - science.org
We present single-molecule, real-time sequencing data obtained from a DNA polymerase
performing uninterrupted template-directed synthesis using four distinguishable …

Methods of amplifying and sequencing nucleic acids

JH Leamon, KL Lohman, JM Rothberg… - US Patent …, 2008 - Google Patents
First worldwide family litigation filed litigation https://patents. darts-ip. com/? family=
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Compositions and methods for molecular labeling

M Samuels, JC Olson, A Watson, K Brown… - US Patent …, 2015 - Google Patents
2012-05-08 Assigned to RAINDANCE TECHNOLOGIES, INC. reassignment RAINDANCE
TECHNOLOGIES, INC. ASSIGNMENT OF ASSIGNORS INTEREST (SEE DOCUMENT FOR …

Fluorescent nucleotide analogs and uses therefor

Y Xu, J Wegener, A Bibillo - US Patent 7,405,281, 2008 - Google Patents
The present invention is generally directed to compositions that comprise compounds that
are analogous to nucleotides, and which, in preferred aspects are readily processible by …

Method of sequencing a nucleic acid

JM Rothberg, JS Bader, SB Dewell, K McDade… - US Patent …, 2007 - Google Patents
US7244559B2 - Method of sequencing a nucleic acid - Google Patents US7244559B2 -
Method of sequencing a nucleic acid - Google Patents Method of sequencing a nucleic acid …

Compositions and methods for nucleic acid sequencing

K Travers, G Otto, S Turner, C Heiner, C Ma - US Patent 8,153,375, 2012 - Google Patents
Compositions and methods for nucleic acid sequencing include template constructs that
comprise double stranded portions in a partially or completely contiguous constructs, to …

Short cycle methods for sequencing polynucleotides

SN Lapidus, PR Buzby, T Harris - US Patent 7,169,560, 2007 - Google Patents
(60) Provisional application No. 60/547,611, filed on Feb. 5,405,783 A 4/1995 Pirrung et al.
24, 2004, provisional application No. 60/546,277. 5,409,811 A 4/1995 Tabor et al. filed on …

Method of sequencing a nucleic acid

JM Rothberg, JS Bader, SB Dewell, K McDade… - US Patent …, 2007 - Google Patents
Disclosed herein are methods and apparatuses for sequencing a nucleic acid. These
methods permit a very large number of independent sequencing reactions to be arrayed in …

Microfluidic devices and methods of use thereof

D Link, M Weiner, D Marran… - US Patent App. 11/803,101, 2008 - Google Patents
2007-07-31 Assigned to RAINDANCE TECHNOLOGIES, INC. reassignment RAINDANCE
TECHNOLOGIES, INC. ASSIGNMENT OF ASSIGNORS INTEREST (SEE DOCUMENT FOR …