The liver has the ability to repair itself after injury; however, a variety of pathological changes
in the liver can affect its ability to regenerate, and this could lead to liver failure …

Considering the high prevalence and the complex pharmacological management of immune-
mediated inflammatory diseases (IMIDs), the search for new therapeutic approaches for their …

Immunomodulatory therapy has become a promising method for the clinical treatment of
many diseases. Recently, pilot studies revealed that immunomodulatory therapy exhibited …

Mesenchymal stem cells (MSCs) are self-renewable, rapidly proliferating, multipotent stem
cells which reside in almost all post-natal tissues. MSCs possess potent immunoregulatory …

It is of significance to construct the immunomodulatory and osteogenic microenvironment for
three dimension (3D) regeneration of bone tissues. 3D scaffolds, with various chemical …

BACKGROUND Recessive dystrophic epidermolysis bullosa (RDEB) is a rare, devastating,
and life-threatening inherited skin fragility disorder that comes about due to a lack of …

Idiopathic pulmonary fibrosis (IPF) is an interstitial disease of unknown etiology
characterized by progressive pulmonary fibrosis. Pirfenidone and nintedanib are the only …

Purpose: The objective of the study was to investigate efficacy and mechanisms of mouse
adipose-derived mesenchymal stem cell-derived exosomes (mADSC-Exos) in the …

With the outbreak of coronavirus disease (COVID-19) caused by novel severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2), the world has been facing an …

Abstract Bone morphogenetic protein (BMP-2) has been approved by the FDA to promote
bone regeneration, but uncertain osteogenic effect and dose-dependent side effects may …