[HTML][HTML] Effects of sorafenib and quercetin alone or in combination in treating hepatocellular carcinoma: in vitro and in vivo approaches

S Abdu, N Juaid, A Amin, M Moulay, N Miled - Molecules, 2022 - mdpi.com
Sorafenib is the first drug approved to treat advanced hepatocellular carcinoma (HCC) and
continues as the gold-standard therapy against HCC. However, acquired drug resistance …

Vascular contributions to 16p11. 2 deletion autism syndrome modeled in mice

J Ouellette, X Toussay, CH Comin, LF Costa… - Nature …, 2020 - nature.com
While the neuronal underpinnings of autism spectrum disorder (ASD) are being unraveled,
vascular contributions to ASD remain elusive. Here, we investigated postnatal …

[HTML][HTML] Therapeutic effects of crocin alone or in combination with sorafenib against hepatocellular carcinoma: in vivo & in vitro insights

S Abdu, N Juaid, A Amin, M Moulay, N Miled - Antioxidants, 2022 - mdpi.com
This study investigated the therapeutic effects of the phytochemical crocin alone or in
combination with sorafenib both in rats chemically induced with hepatocellular carcinoma …

[PDF][PDF] Molecular imaging of tumor microenvironment to assess the effects of locoregional treatment for hepatocellular carcinoma

Q Chen, AZ Chen, G Jia, J Li, C Zheng… - Hepatology …, 2022 - Wiley Online Library
Liver cancer is one of the leading causes of cancer deaths worldwide. Among all primary
liver cancers, hepatocellular carcinoma (HCC) is the most common type, representing 75 …

[HTML][HTML] Dynamic Contrast-Enhanced Ultrasound in the Prediction of Advanced Hepatocellular Carcinoma Response to Systemic and Locoregional Therapies

L Cerrito, ME Ainora, G Cuccia, L Galasso, I Mignini… - Cancers, 2024 - mdpi.com
Simple Summary Hepatocellular carcinoma (HCC) is sometimes diagnosed at an advanced
stage, with subsequent complex therapeutic efforts combining both locoregional and …

Hepatic arterial bland embolization increases Th17 cell infiltration in a syngeneic rat model of hepatocellular carcinoma

R Avritscher, NH Jo, U Polak, AC Cortes… - CardioVascular and …, 2020 - Springer
Purpose To determine the tumor immune cell landscape after transcatheter arterial bland
embolization (TAE) in a clinically relevant rat hepatocellular carcinoma (HCC) model …

Effect of bead size and doxorubicin loading on tumor cellular injury after transarterial embolization and chemoembolization in a rat model of hepatocellular carcinoma

AC Cortes, H Nishiofuku, U Polak, AA Minhaj… - … , Biology and Medicine, 2022 - Elsevier
Embolic agents used in transarterial embolization for intermediate stage hepatocellular
carcinoma reduce blood flow into tumors and can deliver anticancer drugs. Tumor blood …

Comparative study of evaluating the microcirculatory function status of primary small HCC between the CE (DCE-MRI) and Non-CE (IVIM-DWI) MR Perfusion Imaging

Q Song, Y Guo, X Yao, S Rao, C Qian, D Ye… - Abdominal Radiology, 2021 - Springer
Purpose To compare the difference of evaluating the microcirculatory function status of
primary small HCC between DCE-MRI with two-compartmental pharmacokinetic model and …

Bevacizumab and folic acid dual-targeted gadolinium-carbon dots for fluorescence/magnetic resonance imaging of hepatocellular carcinoma

F Maghsoudinia, MB Tavakoli, RK Samani… - Journal of Drug Delivery …, 2021 - Elsevier
In this study, single-and dual-targeted gadolinium-carbon dots (Gd-CDs) with Bevacizumab
(BEV) and/or folic acid (FA) were developed as dual-modal fluorescence and magnetic …

Evaluation of Hypoxia in Hepatocellular Carcinoma Using Quantitative MRI: Significances, Challenges, and Advances

M Chen, X Zhou, H Cai, D Li, C Song… - Journal of Magnetic …, 2023 - Wiley Online Library
This review aimed to perform a scoping review of promising MRI methods in assessing
tumor hypoxia in hepatocellular carcinoma (HCC). The hypoxic microenvironment and …