The COVID-19 pandemic has given the study of virus evolution and ecology new relevance.
Although viruses were first identified more than a century ago, we likely know less about …

Clinical metagenomic next-generation sequencing (mNGS), the comprehensive analysis of
microbial and host genetic material (DNA and RNA) in samples from patients, is rapidly …

ChAdOx1 nCoV-19/AZD1222 is an approved adenovirus-based vaccine for severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2) currently being deployed globally …

Effective therapies to treat coronavirus disease 2019 (COVID-19) are urgently needed.
While many investigational, approved, and repurposed drugs have been suggested as …

The great majority of globally circulating pathogens go undetected, undermining patient care
and hindering outbreak preparedness and response. To enable routine surveillance and …

Here we describe the complete genome of a new ebolavirus, Bombali virus (BOMV)
detected in free-tailed bats in Sierra Leone (little free-tailed (Chaerephon pumilus) and …

The rapid development of next-generation sequencing (NGS) technology, including
advances in sequencing chemistry, sequencing technologies, bioinformatics, and data …

Our recent experience of the COVID-19 pandemic has highlighted the importance of easy-to-
use, quick, cheap, sensitive and selective detection of virus pathogens for the efficient …

Context.—Metagenomic sequencing can be used for detection of any pathogens using
unbiased, shotgun next-generation sequencing (NGS), without the need for sequence …

Next-generation sequencing (NGS) technologies have become increasingly available for
use in the clinical microbiology diagnostic environment. There are three main applications of …