Obesity leads to chronic, systemic inflammation and can lead to insulin resistance (IR), β-cell
dysfunction, and ultimately type 2 diabetes (T2D). This chronic inflammatory state …

Nonalcoholic fatty liver disease (NAFLD) has emerged as the most common chronic liver
disease worldwide and is strongly associated with the presence of oxidative stress …

Here we present an extensive narrative review of the broadly understood modifications to
the lifestyles of women with polycystic ovary syndrome (PCOS). The PubMed database was …

The worldwide obesity epidemic has emerged as a major cause of insulin resistance and
Type 2 diabetes. Chronic tissue inflammation is a well-recognized feature of obesity, and the …

Diet-derived fatty acids (FAs) are essential sources of energy and fundamental structural
components of cells. They also play important roles in the modulation of immune responses …

Abstract Background Oxidative stress (OxS) and mitochondrial dysfunction are implicated as
causative factors for aging. Older adults (OAs) have an increased prevalence of elevated …

Obesity mediates most of its direct medical sequelae through the development of insulin
resistance (IR). The cellular effects of insulin occur through two main postreceptor pathways …

Abstract Background Elevated oxidative stress (OxS), mitochondrial dysfunction, and
hallmarks of aging are identified as key contributors to aging, but improving/reversing these …

Oxidative stress is characterized by an imbalance between prooxidant and antioxidant
species, leading to macromolecular damage and disruption of redox signaling and cellular …

Prolonged periods of skeletal muscle inactivity or mechanical unloading (bed rest, hindlimb
unloading, immobilization, spaceflight and reduced step) can result in a significant loss of …