The percentage of people affected by overweight, obesity and/or diabetes drastically
increased within the last decades. This development is still ongoing, which puts a large part …

Obesity is a chronic condition associated with dyslipidemia and insulin resistance. Here, we
show that the offspring of obese mothers are dyslipidemic and insulin resistant from the …

We intended to examine the molecular mechanism of action of isorhamnetin (IHN) to
regulate the pathway of insulin signaling. Molecular analysis, immunofluorescence, and …

Accumulating evidence indicates that adipose tissue inflammation and mitochondrial
dysfunction in skeletal muscle are inextricably linked to obesity and insulin resistance …

Type-2 diabetes mellitus (T2DM), the leading global health burden of this century majorly
develops due to obesity and hyperglycemia-induced oxidative stress in skeletal muscles …

Background and aims There is significant overlap between non-alcoholic fatty liver disease
(NAFLD) and alcohol-associated liver disease (ALD) with regards to risk factors and disease …

Insulin resistance is associated with the occurrence of stroke and atherosclerotic disease.
However, the relationship between insulin resistance and the prognosis of acute ischemic …

Abstract Purpose of Review Anti-hypertensive and lipid lowering therapy addresses only
half of the cardiovascular disease risk in patients with body mass index> 30 kg/m2, ie …

Polycystic ovarian syndrome (PCOS) is a reproductive, endocrine, and metabolic disorder.
Circulating markers of oxidative stress are abnormal in women with PCOS. There is a close …

Despite rigorous endeavors, existing attempts to handle type 2 diabetes (T2DM) are still a
long way off, as a substantial number of patients do not meet therapeutic targets. Insulin …