Effects of Avocado Oil Supplementation on Insulin Sensitivity, Cognition, and Inflammatory and Oxidative Stress Markers in Different Tissues of Diet-Induced Obese …

S de Oliveira Marques, AP Muller, TF Luciano… - Nutrients, 2022 - mdpi.com
Obesity induces insulin resistance, chronic inflammation, oxidative stress, and
neurocognitive impairment. Avocado oil (AO) has antioxidants and anti-inflammatory effects …

The effects of polyphenol supplementation on adipose tissue morphology and gene expression in overweight and obese humans

J Most, I Warnke, MV Boekschoten, JWE Jocken… - Adipocyte, 2018 - Taylor & Francis
Dietary polyphenols have beneficial effects on adipose tissue mass and function in rodents,
but human studies are scarce. In a randomized, placebo-controlled study, 25 (10 women) …

Mechanism and potential of egg consumption and egg bioactive components on type-2 diabetes

X Wang, M Son, C Meram, J Wu - Nutrients, 2019 - mdpi.com
Type-2 diabetes (T2D) is one of the major global health challenges and a substantial
economic burden. Egg and egg-derived components have been indicated to possess …

A narrative review of non-pharmacological strategies for managing sarcopenia in older adults with cardiovascular and metabolic diseases

T Ispoglou, O Wilson, D McCullough, L Aldrich… - Biology, 2023 - mdpi.com
Simple Summary This article explores the relationship between sarcopenia, cardiovascular
disease and metabolic diseases. The authors suggest non-drug treatments such as …

Mitochondrial transfer restores impaired liver functions by AMPK/mTOR/PI3K-AKT pathways in metabolic syndrome

S Paliwal, S Jain, P Mudgal, K Verma, S Paliwal… - Life Sciences, 2023 - Elsevier
Aim We investigated the effect of mitochondria transfer in high fat diet and streptozotocin
(HFD+ STZ) induced metabolic syndrome (MeS) in rats. The effect of mitochondria transfer in …

Mitochondrial proteostasis as a shared characteristic of slowed aging: the importance of considering cell proliferation

KL Hamilton, BF Miller - The Journal of physiology, 2017 - Wiley Online Library
Proteostasis is one of the seven “pillars of aging research” identified by the Trans‐NIH
Geroscience Initiative and loss of proteostasis is associated with aging and age‐related …

Metformin ameliorates skeletal muscle atrophy in Grx1 KO mice by regulating intramuscular lipid accumulation and glucose utilization

Y Yang, Z Liao, Q Xiao - Biochemical and Biophysical Research …, 2020 - Elsevier
Skeletal muscle is the largest tissue in the body, and plays a remarkable role in energy and
metabolic homeostasis. Disorder in lipid metabolism and glucose utilization could impair the …

Relationship between lipid accumulation product and new-onset diabetes in the Japanese population: a retrospective cohort study

T Liu, W Lu, X Zhao, T Yao, B Song, H Fan… - Frontiers in …, 2023 - frontiersin.org
Background Diabetes has become a global public health problem. Obesity has been
established as a risk factor for diabetes. However, it remains unclear which of the obesity …

3, 3′, 4, 5′-Tetramethoxy-trans-stilbene improves insulin resistance by activating the IRS/PI3K/Akt pathway and inhibiting oxidative stress

Y Tan, L Miao, J Xiao, WS Cheang - Current Issues in Molecular Biology, 2022 - mdpi.com
The potential anti-diabetic effect of resveratrol derivative, 3, 3′, 4, 5′-tetramethoxy-trans-
stilbene (3, 3′, 4, 5′-TMS) and its underlying mechanism in high glucose (HG) and …

Cytosolic lipid excess-induced mitochondrial dysfunction is the cause or effect of high fat diet-induced skeletal muscle insulin resistance: A molecular insight

BA Jana, PK Chintamaneni, PT Krishnamurthy… - Molecular biology …, 2019 - Springer
Mitochondria play a central role in the energy homeostasis in eukaryotic cells by generating
ATP via oxidative metabolism of nutrients. Excess lipid accumulation and impairments in …