Advances in the field of intranasal oxytocin research: lessons learned and future directions for clinical research

DS Quintana, A Lischke, S Grace, D Scheele… - Molecular …, 2021 - nature.com
Reports on the modulatory role of the neuropeptide oxytocin on social cognition and
behavior have steadily increased over the last two decades, stimulating considerable …

Advances in human oxytocin measurement: challenges and proposed solutions

BA Tabak, G Leng, A Szeto, KJ Parker… - Molecular …, 2023 - nature.com
Oxytocin, a neuropeptide known for its role in reproduction and socioemotional processes,
may hold promise as a therapeutic agent in treating social impairments in patient …

Brain oxytocin: how puzzle stones from animal studies translate into psychiatry

V Grinevich, ID Neumann - Molecular psychiatry, 2021 - nature.com
The neuropeptide oxytocin has attracted great attention of the general public, basic
neuroscience researchers, psychologists, and psychiatrists due to its profound pro-social …

Intranasal oxytocin: myths and delusions

G Leng, M Ludwig - Biological psychiatry, 2016 - Elsevier
Despite widespread reports that intranasal application of oxytocin has a variety of behavioral
effects, very little of the huge amounts applied intranasally appears to reach the …

Novel noninvasive approaches to the treatment of obesity: from pharmacotherapy to gene therapy

AM Angelidi, MJ Belanger, A Kokkinos… - Endocrine …, 2022 - academic.oup.com
Recent insights into the pathophysiologic underlying mechanisms of obesity have led to the
discovery of several promising drug targets and novel therapeutic strategies to address the …

The biology of mammalian parenting and its effect on offspring social development

JK Rilling, LJ Young - Science, 2014 - science.org
Parents know the transformative nature of having and caring for a child. Among many
mammals, giving birth leads from an aversion to infant stimuli to irresistible attraction. Here …

Intranasal insulin for Alzheimer's disease

M Hallschmid - CNS drugs, 2021 - Springer
Brain insulin signaling contributes to memory function and might be a viable target in the
prevention and treatment of memory impairments including Alzheimer's disease. This short …

Roles of oxytocin in stress responses, allostasis and resilience

Y Takayanagi, T Onaka - International journal of molecular sciences, 2021 - mdpi.com
Oxytocin has been revealed to work for anxiety suppression and anti-stress as well as for
psychosocial behavior and reproductive functions. Oxytocin neurons are activated by …

Kinetics and dose dependency of intranasal oxytocin effects on amygdala reactivity

FB Spengler, J Schultz, D Scheele, M Essel, W Maier… - Biological …, 2017 - Elsevier
Background Current neuroimaging perspectives on a variety of mental disorders emphasize
dysfunction of the amygdala. The neuropeptide oxytocin (OXT), a key mediator in the …

The correlation between central and peripheral oxytocin concentrations: a systematic review and meta-analysis

M Valstad, GA Alvares, M Egknud… - Neuroscience & …, 2017 - Elsevier
There is growing interest in the role of the oxytocin system in social cognition and behavior.
Peripheral oxytocin concentrations are regularly used to approximate central concentrations …