Lipoprotein (a) and its significance in cardiovascular disease: a review
FD Lau, RP Giugliano - Jama Cardiology, 2022 - jamanetwork.com
Importance Lipoprotein (a)(Lp [a]) is a low-density lipoprotein (LDL) cholesterol–like particle
bound to apolipoprotein (a). This novel marker of cardiovascular disease acts through …
bound to apolipoprotein (a). This novel marker of cardiovascular disease acts through …
A test in context: lipoprotein (a) diagnosis, prognosis, controversies, and emerging therapies
S Tsimikas - Journal of the American College of Cardiology, 2017 - jacc.org
Evidence that elevated lipoprotein (a)(Lp [a]) levels contribute to cardiovascular disease
(CVD) and calcific aortic valve stenosis (CAVS) is substantial. Development of isoform …
(CVD) and calcific aortic valve stenosis (CAVS) is substantial. Development of isoform …
Lipoprotein (a) and cardiovascular disease
PR Kamstrup - Clinical chemistry, 2021 - academic.oup.com
Background High lipoprotein (a) concentrations present in 10%–20% of the population have
long been linked to increased risk of ischemic cardiovascular disease. It is unclear whether …
long been linked to increased risk of ischemic cardiovascular disease. It is unclear whether …
[HTML][HTML] Structure, function, and genetics of lipoprotein (a)
K Schmidt, A Noureen, F Kronenberg… - Journal of lipid …, 2016 - ASBMB
Lipoprotein (a)[Lp (a)] has attracted the interest of researchers and physicians due to its
intriguing properties, including an intragenic multiallelic copy number variation in the LPA …
intriguing properties, including an intragenic multiallelic copy number variation in the LPA …
[HTML][HTML] HEART UK consensus statement on Lipoprotein (a): A call to action
J Cegla, RDG Neely, M France, G Ferns, CD Byrne… - Atherosclerosis, 2019 - Elsevier
Abstract Lipoprotein (a), Lp (a), is a modified atherogenic low-density lipoprotein particle that
contains apolipoprotein (a). Its levels are highly heritable and variable in the population …
contains apolipoprotein (a). Its levels are highly heritable and variable in the population …
[HTML][HTML] Lipoprotein (a) beyond the kringle IV repeat polymorphism: the complexity of genetic variation in the LPA gene
S Coassin, F Kronenberg - Atherosclerosis, 2022 - Elsevier
Abstract High lipoprotein (a)[Lp (a)] concentrations are one of the most important genetically
determined risk factors for cardiovascular disease. Lp (a) concentrations are an enigmatic …
determined risk factors for cardiovascular disease. Lp (a) concentrations are an enigmatic …
[HTML][HTML] Lipoprotein (a) as a cause of cardiovascular disease: insights from epidemiology, genetics, and biology
BG Nordestgaard, A Langsted - Journal of lipid research, 2016 - ASBMB
Human epidemiologic and genetic evidence using the Mendelian randomization approach
in large-scale studies now strongly supports that elevated lipoprotein (a)[Lp (a)] is a causal …
in large-scale studies now strongly supports that elevated lipoprotein (a)[Lp (a)] is a causal …
Phenotypic characterization of genetically lowered human lipoprotein (a) levels
Background: Genomic analyses have suggested that the LPA gene and its associated
plasma biomarker, lipoprotein (a)(Lp [a]), represent a causal risk factor for coronary heart …
plasma biomarker, lipoprotein (a)(Lp [a]), represent a causal risk factor for coronary heart …
[HTML][HTML] Apolipoprotein (a) isoform size, lipoprotein (a) concentration, and coronary artery disease: a mendelian randomisation analysis
Background The lipoprotein (a) pathway is a causal factor in coronary heart disease. We
used a genetic approach to distinguish the relevance of two distinct components of this …
used a genetic approach to distinguish the relevance of two distinct components of this …
Japan Atherosclerosis Society (JAS) Guidelines for prevention of atherosclerotic cardiovascular diseases 2022
T Okamura, K Tsukamoto, H Arai, Y Fujioka… - … of Atherosclerosis and …, 2024 - jstage.jst.go.jp
In Japan, a super-aged society, deaths from atherosclerotic cardiovascular disease
(ASCVD), especially cardiac diseases including coronary artery disease (CAD) such as …
(ASCVD), especially cardiac diseases including coronary artery disease (CAD) such as …