Lipoprotein (a)-related cardiovascular and all-cause mortalities in Korean adults

BJ Kim, MY Lee, HI Choi, MJ Kwon… - European Journal of …, 2023 - academic.oup.com
Aims There are inconsistent results on the association between lipoprotein (a) and mortality-
related outcomes due to a lack of evidence from large-scale observational studies of Asians …

Investigation of a nonsense mutation located in the complex KIV-2 copy number variation region of apolipoprotein (a) in 10,910 individuals

S Di Maio, R Grüneis, G Streiter, C Lamina… - Genome medicine, 2020 - Springer
Background The concentrations of the highly atherogenic lipoprotein (a)[Lp (a)] are mainly
genetically determined by the LPA gene locus. However, up to 70% of the coding sequence …

Progress in the care of common inherited atherogenic disorders of apolipoprotein B metabolism

KL Ellis, AJ Hooper, JR Burnett, GF Watts - Nature Reviews …, 2016 - nature.com
Familial hypercholesterolaemia, familial combined hyperlipidaemia (FCH) and elevated
lipoprotein (a) are common, inherited disorders of apolipoprotein B metabolism that …

History of lipidology and lipoprotein apheresis

U Julius - Atherosclerosis Supplements, 2017 - Elsevier
This review tells the story of atherosclerosis research in the beginning of the 20th century. It
presents the significance of cardiovascular diseases and addresses major questions …

Genetics and Pathophysiological Mechanisms of Lipoprotein (a)‐Associated Cardiovascular Risk

AS Volgman, ML Koschinsky, A Mehta… - Journal of the …, 2024 - Am Heart Assoc
Elevated lipoprotein (a) is a genetically transmitted codominant trait that is an independent
risk driver for cardiovascular disease. Lipoprotein (a) concentration is heavily influenced by …

Lipoprotein (a) as a predictor of early stroke recurrence in acute ischemic stroke

XW Hong, DM Wu, J Lu, YL Zheng, WJ Tu… - Molecular Neurobiology, 2018 - Springer
Inflammation plays a crucial role in the pathogenesis of stroke. This study aims to determine
lipoprotein (a)[Lp (a)] levels in serum and to investigate their associations with stroke …

Lipoprotein (a)-Related Inflammatory Imbalance: A Novel Horizon for the Development of Atherosclerosis

T Qin, TY Ma, K Huang, SJ Lu, JH Zhong… - Current Atherosclerosis …, 2024 - Springer
Abstract Purpose of Review The primary objective of this review is to explore the
pathophysiological roles and clinical implications of lipoprotein (a)[Lp (a)] in the context of …

Novel biomarkers for cardiovascular risk assessment: current status and future directions

J MacNamara, DJ Eapen, A Quyyumi… - Future cardiology, 2015 - Taylor & Francis
Cardiovascular disease (CVD) is the leading cause of mortality in the modern world.
Traditional risk algorithms may miss up to 20% of CVD events. Therefore, there is a need for …

A decade of progress on the genetic basis of coronary artery disease. Practical insights for the internist

D Girelli, C Piubelli, N Martinelli, R Corrocher… - European Journal of …, 2017 - Elsevier
Clinicians are well aware of the importance of a positive family history for coronary artery
disease (CAD). Nonetheless, elucidation of the genetic basis of CAD has long proven …

Associations between common and rare exonic genetic variants and serum levels of 20 cardiovascular-related proteins: the Tromsø Study

T Solomon, EN Smith, H Matsui… - Circulation …, 2016 - Am Heart Assoc
Background—Genetic variation can be used to study causal relationships between
biomarkers and diseases. Here, we identify new common and rare genetic variants …