Compared with conventional chemotherapy and targeted therapy, immunotherapy has
changed the treatment prospects of various solid tumors and has recently become the main …

Colorectal cancer (CRC) is one of the most common cancers worldwide. Current therapies
such as surgery, chemotherapy, and radiotherapy encounter obstacles in preventing …

Dendritic cells (DCs) occupy a central position in the immune system, orchestrating a wide
repertoire of responses that span from the development of self-tolerance to the elicitation of …

Morphology tuning is a potent strategy to modulate physiological effects of synthetic
biomaterials, but it is rarely explored in microbe-based biochemicals due to the lack of …

Therapeutic cancer vaccines aim to generate immunologic targeting of cancer cells through
the induction of effective cellular and antibody-mediated responses specific for antigens …

Purpose: Mesothelioma has been regarded as a nonimmunogenic tumor, which is also
shown by the low response rates to treatments targeting the PD-1/PD-L1 axis. Previously …

Background Immune-mediated therapies have transformed the treatment of metastatic
melanoma and renal, bladder, and both small and non-small cell lung carcinomas …

There are increasing incidences and mortality rates for colorectal cancer in the world. It is
common for chemotherapy and radiation given to patients with colorectal cancer to cause …

Purpose: This study characterizes, biologically and clinically, a novel type of dendritic cells
(DC) produced in the short term and called tumor antigen–presenting cells (TAPCells). In …

Background Autologous tumour lysate dendritic cell vaccine (ADC) has T-cell stimulatory
capacity and, therefore, potential antitumour activity. We designed a phase II randomised …