Bacteria in cancer initiation, promotion and progression

G El Tekle, WS Garrett - Nature Reviews Cancer, 2023 - nature.com
Cancer cells originate from a series of acquired genetic mutations that can drive their
uncontrolled cell proliferation and immune evasion. Environmental factors, including the …

Impact of gut microbiome on skin health: gut-skin axis observed through the lenses of therapeutics and skin diseases

MR Mahmud, S Akter, SK Tamanna, L Mazumder… - Gut …, 2022 - Taylor & Francis
The human intestine hosts diverse microbial communities that play a significant role in
maintaining gut-skin homeostasis. When the relationship between gut microbiome and the …

Epithelial barrier hypothesis: effect of the external exposome on the microbiome and epithelial barriers in allergic disease

Z Celebi Sozener, B Ozdel Ozturk, P Cerci, M Turk… - Allergy, 2022 - Wiley Online Library
Environmental exposure plays a major role in the development of allergic diseases. The
exposome can be classified into internal (eg, aging, hormones, and metabolic processes) …

Pathogenesis and virulence of Candida albicans

JP Lopes, MS Lionakis - Virulence, 2022 - Taylor & Francis
Candida albicans is a commensal yeast fungus of the human oral, gastrointestinal, and
genital mucosal surfaces, and skin. Antibiotic-induced dysbiosis, iatrogenic …

Staphylococcus epidermidis and its dual lifestyle in skin health and infection

MM Severn, AR Horswill - Nature Reviews Microbiology, 2023 - nature.com
The coagulase-negative bacterium Staphylococcus epidermidis is a member of the human
skin microbiota. S. epidermidis is not merely a passive resident on skin but actively primes …

Wound healing: cellular mechanisms and pathological outcomes

HN Wilkinson, MJ Hardman - Open biology, 2020 - royalsocietypublishing.org
Wound healing is a complex, dynamic process supported by a myriad of cellular events that
must be tightly coordinated to efficiently repair damaged tissue. Derangement in wound …

Interaction between microbiota and immunity in health and disease

D Zheng, T Liwinski, E Elinav - Cell research, 2020 - nature.com
The interplay between the commensal microbiota and the mammalian immune system
development and function includes multifold interactions in homeostasis and disease. The …

The roles of CD8+ T cell subsets in antitumor immunity

MS Paul, PS Ohashi - Trends in cell biology, 2020 - cell.com
Effector CD8+ T cells are typically thought to be a homogenous group of cytotoxic cells that
produce interferon-(IFN) γ. However, recent findings have challenged this notion because …

The immune functions of keratinocytes in skin wound healing

M Piipponen, D Li, NX Landén - International journal of molecular …, 2020 - mdpi.com
As the most dominant cell type in the skin, keratinocytes play critical roles in wound repair
not only as structural cells but also exerting important immune functions. This review focuses …

Development of a human skin commensal microbe for bacteriotherapy of atopic dermatitis and use in a phase 1 randomized clinical trial

T Nakatsuji, TR Hata, Y Tong, JY Cheng, F Shafiq… - Nature medicine, 2021 - nature.com
Staphylococcus aureus colonizes patients with atopic dermatitis (AD) and exacerbates
disease by promoting inflammation. The present study investigated the safety and …