Aptamer–protein interactions: from regulation to biomolecular detection

C Ji, J Wei, L Zhang, X Hou, J Tan, Q Yuan… - Chemical …, 2023 - ACS Publications
Serving as the basis of cell life, interactions between nucleic acids and proteins play
essential roles in fundamental cellular processes. Aptamers are unique single-stranded …

Hybridization chain reaction: a versatile molecular tool for biosensing, bioimaging, and biomedicine

S Bi, S Yue, S Zhang - Chemical Society Reviews, 2017 - pubs.rsc.org
Developing powerful, simple and low-cost DNA amplification techniques is of great
significance to bioanalysis and biomedical research. Thus far, many signal amplification …

Synthesis, bioactive properties, and biomedical applications of intrinsically therapeutic nanoparticles for disease treatment

DD Nguyen, JY Lai - Chemical Engineering Journal, 2022 - Elsevier
Intrinsically therapeutic nanoparticles (ITNPs) are a special class of nanomaterials with
capabilities of self-triggering bioactive activities (without drug) when interacting with …

Functional nucleic acid-based hydrogels for bioanalytical and biomedical applications

J Li, L Mo, CH Lu, T Fu, HH Yang, W Tan - Chemical Society Reviews, 2016 - pubs.rsc.org
Hydrogels are crosslinked hydrophilic polymers that can absorb a large amount of water. By
their hydrophilic, biocompatible and highly tunable nature, hydrogels can be tailored for …

Magnetic nanoparticle facilitated drug delivery for cancer therapy with targeted and image‐guided approaches

J Huang, Y Li, A Orza, Q Lu, P Guo… - Advanced functional …, 2016 - Wiley Online Library
With rapid advances in nanomedicine, magnetic nanoparticles (MNPs) have emerged as a
promising theranostic tool in biomedical applications, including diagnostic imaging, drug …

Aptamers in biomedicine: Selection strategies and recent advances

G Ștefan, O Hosu, K De Wael, MJ Lobo-Castañón… - Electrochimica …, 2021 - Elsevier
Aptamers have come in the spotlight as bio-mimetic molecular recognition elements in the
field of biomedicine due to various applications in diagnostics, drug delivery, therapeutics …

[HTML][HTML] Dual-stimuli responsive and reversibly activatable theranostic nanoprobe for precision tumor-targeting and fluorescence-guided photothermal therapy

X Zhao, CX Yang, LG Chen, XP Yan - Nature Communications, 2017 - nature.com
The integrated functions of diagnostics and therapeutics make theranostics great potential
for personalized medicine. Stimulus-responsive therapy allows spatial control of therapeutic …

Functional aptamer-embedded nanomaterials for diagnostics and therapeutics

S Xie, L Ai, C Cui, T Fu, X Cheng, F Qu… - ACS applied materials & …, 2021 - ACS Publications
In the past decades, various nanomaterials with unique properties have been explored for
bioapplications. Meanwhile, aptamers, generated from the systematic evolution of ligands by …

Metal-organic frameworks-based sensitive electrochemiluminescence biosensing

J Zhou, Y Li, W Wang, X Tan, Z Lu, H Han - Biosensors and Bioelectronics, 2020 - Elsevier
Metal-organic frameworks (MOFs) as porous materials have attracted much attention in
various fields such as gas storage, catalysis, separation, and nanomedical engineering …

Aptamer-based targeted drug delivery systems: current potential and challenges

F He, N Wen, D Xiao, J Yan, H Xiong… - Current medicinal …, 2020 - ingentaconnect.com
Aptamers are single-stranded DNA or RNA with 20-100 nucleotides in length that can
specifically bind to target molecules via formed three-dimensional structures. These …