Phytochemistry and biological properties of isoprenoid flavonoids from Sophora flavescens Ait

J Li, X Zhang, X Shen, C Xu, C Tan, Y Lin - Fitoterapia, 2020 - Elsevier
Abstract Sophora flavescens Ait (Ku-Shen in Chinese) is a popular traditional Chinese
herbal medicine in China for a long history. It shows significant pharmacological activities in …

Molecular mechanism of the anti-inflammatory effects of Sophorae Flavescentis Aiton identified by network pharmacology

N Zhu, J Hou - Scientific reports, 2021 - nature.com
Inflammation, a protective response against infection and injury, involves a variety of
biological processes. Sophorae Flavescentis (Kushen) is a promising Traditional Chinese …

Fingerprint analysis of Zanthoxylum armatum DC. by HPLC

Z Zhuo, D Xu, Y Li, B Pu, M Ye - Journal of Food Composition and Analysis, 2021 - Elsevier
An effective and comprehensive high-performance liquid chromatography (HPLC) method
was established for fingerprint analysis of Zanthoxylum armatum DC. for the detection of …

Network pharmacology integrated with molecular docking reveals the common experiment-validated antipyretic mechanism of bitter-cold herbs

W Zhou, Y Dai, J Meng, P Wang, Y Wu, L Dai… - Journal of …, 2021 - Elsevier
Ethnopharmacological relevance Bitter-cold herbs have been used to clearing heat and
expelling damp in clinical practice in China for thousands of years. Aim of the study: This …

Preparative Purification of Total Flavonoids from Sophora tonkinensis Gagnep. by Macroporous Resin Column Chromatography and Comparative Analysis of …

M Hou, W Hu, Z Xiu, A Jiang, L Men, K Hao, X Sun… - Molecules, 2019 - mdpi.com
For the full development and utilization of Sophora tonkinensis Gagnep., this study was
primarily intended to established a simple and efficient approach for the preparative …

Integrated metabolomics and network pharmacology strategy for ascertaining the quality marker of flavonoids for Sophora flavescens

L Chen, X Huang, H Wang, J Shao, Y Luo… - … of Pharmaceutical and …, 2020 - Elsevier
Abstract Traditional Chinese medicines (TCMs) have been widely used in Asian countries
for thousands of years due to their supreme quality and good clinical efficacy. However, the …

Development of an eco-friendly and fast HPLC method for quantitative analysis of four nucleosides in Cordyceps and related products

Q Zheng-Ming, WU Zi, Q Huang, W Chuan-Xi… - Chinese Journal of …, 2021 - Elsevier
An eco-friendly and fast HPLC method was developed for the determination of adenosine,
inosine, guanosine and uridine in Cordyceps and related products (fermented mycelia of …

[HTML][HTML] Construction and Chemical Profile on “Activity Fingerprint” of Citri Reticulatae Pericarpium from Different Cultivars Based on HPLC-UV, LC/MS-IT-TOF, and …

G Zheng, Y Chao, M Luo, B Xie, D Zhang… - Evidence-Based …, 2020 - hindawi.com
Citri Reticulatae Pericarpium (CRP), known as Chenpi (CP) in Chinese, is a medicinal food
for health and fitness. In order to find out the characteristic activity chemicals distinguishing …

Protective Effects of Sophorae tonkinensis Gagnep. (Fabaceae) Radix et Rhizoma Water Extract on Carbon Tetrachloride-Induced Acute Liver Injury

C Zhou, A Liu, G Liu, C Yang, Q Zhou, H Li, H Yang… - Molecules, 2022 - mdpi.com
Sophorae tonkinensis Radix et Rhizoma (STR) is a traditional Chinese herbal medicine.
STR can reduce aminotransferase activity; however, the specific mechanism remains …

Lack of Correlation between In Vitro and In Vivo Studies on the Inhibitory Effects of (‒)-Sophoranone on CYP2C9 Is Attributable to Low Oral Absorption and Extensive …

YF Zheng, SH Bae, Z Huang, SU Chae, SJ Jo, HJ Shim… - Pharmaceutics, 2020 - mdpi.com
(‒)-Sophoranone (SPN) is a bioactive component of Sophora tonkinensis with various
pharmacological activities. This study aims to evaluate its in vitro and in vivo inhibitory …